The treatment of acute ischemic stroke continues to advance. The mainstay of treatment
remains intravenous thrombolysis with alteplase. Recent studies demonstrated that later …

Endovascular treatment is a highly effective therapy for acute ischemic stroke due to large
vessel occlusion. However, in clinical practice, nearly half of the patients do not have …

Background The effects and risks of endovascular thrombectomy 6 to 24 hours after stroke
onset due to basilar-artery occlusion have not been extensively studied. Methods In a trial …

Background Endovascular treatment for anterior circulation ischaemic stroke is effective and
safe within a 6 h window. MR CLEAN-LATE aimed to assess efficacy and safety of …

Background: The authors compare the effectiveness and safety of endovascular treatment
(EVT) versus best medical management (BMM) in strokes attributable to acute basilar artery …

Rationale: Mechanical thrombectomy (MT), the standard of care for acute ischemic stroke
(AIS) secondary to large vessel occlusion (LVO), is generally not offered to patients with …

Importance DL-3-n-butylphthalide (NBP) is a drug for treating acute ischemic stroke and may
play a neuroprotective role by acting on multiple active targets. The efficacy of NBP in …

The 2022 update of the Canadian Stroke Best Practice Recommendations (CSBPR) for
Acute Stroke Management, 7th edition, is a comprehensive summary of current evidence …

Background and hypothesis: Recently, two multicenter randomized controlled trials (RCT)
failed to show a significantly beneficial effect of endovascular treatment (EVT) in patients …

Abstract During the last 5–7 years, tremendous progress was achieved in the reperfusion
treatment of acute ischaemic stroke during its first few hours from symptom onset. This …