Dengue is a highly endemic infectious disease of the tropical countries and is rapidly
becoming a global burden. It is caused by any of the 4 serotypes of dengue virus and is …

Flaviviruses are enveloped, single-stranded RNA viruses that widely infect many animal
species. The envelope protein, a structural protein of flavivirus, plays an important role in …

Approximately 100–400 million people from more than 100 countries in the tropical and
subtropical world are affected by dengue infections. Recent scientific breakthroughs have …

Most areas of the globe are endemic for at least one flavivirus, putting billions at risk for
infection. This diverse group of viral pathogens causes a range of manifestations in humans …

Dengue virus is an arbovirus belonging to class Flaviviridae Its clinical manifestation ranges
from asymptomatic to extreme conditions (dengue hemorrhagic fever/dengue shock …

Recombinant proteins are gaining enormous importance these days due to their wide
application as biopharmaceutical products and proven safety record. Various recombinant …

Traditionally, the four dengue virus serotypes have been associated with fever, rash, and the
more severe forms, haemorrhagic fever and shock syndrome. As our knowledge as well as …

Dengue is the most important arthropod-borne viral disease of humans, with more than half
of the global population living in at-risk areas. Despite the negative impact on public health …

The pathogenesis of dengue is likely to be a complex interplay of host immunity and genetic
predisposition combined with certain viral virulence factors. Better understanding of the …

The Flaviviridae virus family was named after the Yellow-fever virus, and the latin term flavi
means “of golden color”. Dengue, caused by Dengue virus (DENV), is one of the most …