Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications

J Ren, NN Wu, S Wang, JR Sowers… - Physiological …, 2021 - journals.physiology.org
The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

Relevance of leptin and other adipokines in obesity-associated cardiovascular risk

MF Landecho, C Tuero, V Valentí, I Bilbao… - Nutrients, 2019 - mdpi.com
Obesity, which is a worldwide epidemic, confers increased risk for multiple serious
conditions including type 2 diabetes, nonalcoholic fatty liver disease, and cardiovascular …

Adiponectin-leptin ratio is a functional biomarker of adipose tissue inflammation

G Frühbeck, V Catalán, A Rodríguez, B Ramírez… - Nutrients, 2019 - mdpi.com
Obesity favors the development of cardiometabolic alterations such as type 2 diabetes (T2D)
and the metabolic syndrome (MS). Obesity and the MS are distinguished by an increase in …

Overview and new insights into the metabolic syndrome: risk factors and emerging variables in the development of type 2 diabetes and cerebrocardiovascular disease

MR Hayden - Medicina, 2023 - mdpi.com
Metabolic syndrome (MetS) is considered a metabolic disorder that has been steadily
increasing globally and seems to parallel the increasing prevalence of obesity. It consists of …

Serum leptin, resistin, and adiponectin levels in obese and non-obese patients with newly diagnosed type 2 diabetes mellitus: a population-based study

W Liu, X Zhou, Y Li, S Zhang, X Cai, R Zhang, S Gong… - Medicine, 2020 - journals.lww.com
Disturbances in adipocytokine profiles can contribute to peripheral insulin resistance and
impairment of insulin production, which are 2 primary pathophysiological mechanisms …

Vitamin D in osteosarcopenic obesity

L Di Filippo, R De Lorenzo, A Giustina… - Nutrients, 2022 - mdpi.com
Osteosarcopenic obesity is a unique clinical condition where low bone and muscle mass
coexist in individuals with obesity. Alterations in adipose tissue, skeletal muscle and bone …

Natural bioactive compounds useful in clinical management of metabolic syndrome

A Noce, M Di Lauro, F Di Daniele… - Nutrients, 2021 - mdpi.com
Metabolic syndrome (MetS) is a clinical manifestation characterized by a plethora of
comorbidities, including hyperglycemia, abdominal obesity, arterial hypertension, and …

Towards an adiposity-related disease framework for the diagnosis and management of obesities

CM Perdomo, I Avilés-Olmos, D Dicker… - Reviews in Endocrine …, 2023 - Springer
Obesity is a complex disease that relapses frequently and associates with multiple
complications that comprise a worldwide health priority because of its rising prevalence and …

Diabetes mellitus, energy metabolism, and COVID-19

C Conte, E Cipponeri, M Roden - Endocrine Reviews, 2024 - academic.oup.com
Obesity, diabetes mellitus (mostly type 2), and COVID-19 show mutual interactions because
they are not only risk factors for both acute and chronic COVID-19 manifestations, but also …

Natural dietary and medicinal plants with anti-obesity therapeutics activities for treatment and prevention of obesity during lock down and in post-COVID-19 era

W Sun, MH Shahrajabian, Q Cheng - Applied Sciences, 2021 - mdpi.com
Overweight and obesity have become global epidemics, especially during the lockdown due
to the COVID-19 pandemic. The potential of medicinal plants as a better and safe option in …