Epigenetic regulation of aging: implications for interventions of aging and diseases

K Wang, H Liu, Q Hu, L Wang, J Liu, Z Zheng… - Signal transduction and …, 2022 - nature.com
Aging is accompanied by the decline of organismal functions and a series of prominent
hallmarks, including genetic and epigenetic alterations. These aging-associated epigenetic …

Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

An examination and critique of current methods to determine exercise intensity

NA Jamnick, RW Pettitt, C Granata, DB Pyne… - Sports Medicine, 2020 - Springer
Prescribing the frequency, duration, or volume of training is simple as these factors can be
altered by manipulating the number of exercise sessions per week, the duration of each …

Physiological adaptations to interval training and the role of exercise intensity

MJ MacInnis, MJ Gibala - The Journal of physiology, 2017 - Wiley Online Library
Interval exercise typically involves repeated bouts of relatively intense exercise interspersed
by short periods of recovery. A common classification scheme subdivides this method into …

Training-induced changes in mitochondrial content and respiratory function in human skeletal muscle

C Granata, NA Jamnick, DJ Bishop - Sports Medicine, 2018 - Springer
A sedentary lifestyle has been linked to a number of metabolic disorders that have been
associated with sub-optimal mitochondrial characteristics and an increased risk of …

Evidence-based effects of high-intensity interval training on exercise capacity and health: A review with historical perspective

MM Atakan, Y Li, ŞN Koşar, HH Turnagöl… - International journal of …, 2021 - mdpi.com
Engaging in regular exercise results in a range of physiological adaptations offering benefits
for exercise capacity and health, independent of age, gender or the presence of chronic …

Metabolism of ketone bodies during exercise and training: physiological basis for exogenous supplementation

M Evans, KE Cogan, B Egan - The Journal of physiology, 2017 - Wiley Online Library
Optimising training and performance through nutrition strategies is central to supporting elite
sportspeople, much of which has focused on manipulating the relative intake of …

High-intensity exercise and mitochondrial biogenesis: current controversies and future research directions

DJ Bishop, J Botella, AJ Genders, MJC Lee… - …, 2019 - journals.physiology.org
It is well established that different types of exercise can provide a powerful stimulus for
mitochondrial biogenesis. However, there are conflicting findings in the literature, and a …

[HTML][HTML] Exercise metabolism and the molecular regulation of skeletal muscle adaptation

B Egan, JR Zierath - Cell metabolism, 2013 - cell.com
Preservation of aerobic fitness and skeletal muscle strength through exercise training can
ameliorate metabolic dysfunction and prevent chronic disease. These benefits are mediated …

Exercise and mitochondrial health

JM Memme, AT Erlich, G Phukan… - The Journal of …, 2021 - Wiley Online Library
Mitochondrial health is an important mediator of cellular function across a range of tissues,
and as a result contributes to whole‐body vitality in health and disease. Our understanding …