Osteoarthritis (OA) is a progressive and disabling musculoskeletal disease affecting millions
of people and resulting in major healthcare costs worldwide. It is the most common form of …

Articular cartilage shows limited self-healing ability owing to its low cellularity and
avascularity. Untreated cartilage defects display an increased propensity to degenerate …

Osteoarthritis (OA) has been recognized as an age-related degenerative disease commonly
seen in the elderly that affects the whole “organ” including cartilage, subchondral bone …

With the global increase of the elderly population, the improvement of the treatment for
various aging-related diseases and the extension of a healthy lifespan have become some …

Osteoarthritis (OA) is a degenerative disease with a series of metabolic changes
accompanied by many altered enzymes. Here, we report that the down-regulated …

Imaging techniques for quantifying changes in the hierarchical structure of deforming joints
are constrained by destructive sample treatments, sample-size restrictions and lengthy scan …

Osteoarthritis (OA) is increasingly recognised as a disease of diverse phenotypes with
variable clinical presentation, progression, and response to therapeutic intervention. This …

Cartilage homeostasis is essential for chondrocytes to maintain proper phenotype and
metabolism. Because adult articular cartilage is avascular, chondrocytes must survive in low …

Osteoarthritis (OA) is a chronic degenerative osteoarthropathy. Although it has been
revealed that a variety of factors can cause or aggravate the symptoms of OA, the …

Osteoarthritis (OA) is one of the most common chronic conditions in the world today. It results
in breakdown of cartilage in joints and causes the patient to experience intense pain and …