[HTML][HTML] Circadian biology to advance therapeutics for mood disorders

A Bhatnagar, G Murray, S Ray - Trends in Pharmacological Sciences, 2023 - cell.com
Mood disorders account for a significant global disease burden, and pharmacological
innovation is needed as existing medications are suboptimal. A wide range of evidence …

Neurological and psychiatric comorbidities of migraine: concepts and future perspectives

N Pelzer, I de Boer… - …, 2023 - journals.sagepub.com
Background This narrative review aims to discuss several common neurological and
psychiatric disorders that show comorbidity with migraine. Not only can we gain …

[图书][B] The American psychiatric association publishing textbook of psychopharmacology

AF Schatzberg, CB Nemeroff - 2017 - books.google.com
The American Psychiatric Association Publishing Textbook of Psychopharmacology is an
indispensable and comprehensive resource for clinicians and trainees who prescribe …

Anhedonia in depression and bipolar disorder

AE Whitton, DA Pizzagalli - Anhedonia: Preclinical, Translational, and …, 2022 - Springer
Anhedonia is a hallmark feature of depression and is highly prevalent among individuals
with mood disorders. The history and neurobiology of anhedonia has been most extensively …

Lithium response in bipolar disorder: Genetics, genomics, and beyond

S Papiol, TG Schulze, U Heilbronner - Neuroscience letters, 2022 - Elsevier
Lithium is an effective mood stabilizer in bipolar disorder (BD). There is, however, high
variability in treatment response to lithium and only 20–30% of individuals with BD are …

Why lithium should be used in patients with bipolar disorder? A scoping review and an expert opinion paper

G Sampogna, D Janiri, U Albert, F Caraci… - Expert Review of …, 2022 - Taylor & Francis
Introduction Lithium treatment is considered the gold standard for the long-term
management of bipolar disorder and recurrent unipolar depression. It is also extremely …

New advances in the pharmacology and toxicology of lithium: a neurobiologically oriented overview

A Bortolozzi, G Fico, M Berk, M Solmi, M Fornaro… - Pharmacological …, 2024 - ASPET
Over the last six decades, lithium has been considered the gold standard treatment for the
long-term management of bipolar disorder due to its efficacy in preventing both manic and …

The impact of lithium on circadian rhythms and implications for bipolar disorder pharmacotherapy

KE Rohr, MJ McCarthy - Neuroscience letters, 2022 - Elsevier
Bipolar disorder (BD) is characterized by disrupted circadian rhythms affecting sleep,
arousal, and mood. Lithium is among the most effective mood stabilizer treatments for BD …

Correction of depression‐associated circadian rhythm abnormalities is associated with lithium response in bipolar disorder

M Federoff, MJ McCarthy, A Anand… - Bipolar …, 2022 - Wiley Online Library
Background Bipolar disorder (BD) is characterized by episodes of depression and mania
and disrupted circadian rhythms. Lithium is an effective therapy for BD, but only 30%–40% of …

[HTML][HTML] Divergent directionality of immune cell-specific protein expression between bipolar lithium responders and non-responders revealed by enhanced flow …

K Gao, NM Kaye, M Ayati, M Koyuturk, JR Calabrese… - Medicina, 2023 - mdpi.com
Background and Objectives: There is no biomarker to predict lithium response. This study
used CellPrint™ enhanced flow cytometry to study 28 proteins representing a spectrum of …