Ferroptosis in cancer and cancer immunotherapy
The hallmark of tumorigenesis is the successful circumvention of cell death regulation for
achieving unlimited replication and immortality. Ferroptosis is a newly identified type of cell …
achieving unlimited replication and immortality. Ferroptosis is a newly identified type of cell …
Autophagy mediates an amplification loop during ferroptosis
S Lee, N Hwang, BG Seok, S Lee, SJ Lee… - Cell Death & …, 2023 - nature.com
Ferroptosis, a programmed cell death, has been identified and associated with cancer and
various other diseases. Ferroptosis is defined as a reactive oxygen species (ROS) …
various other diseases. Ferroptosis is defined as a reactive oxygen species (ROS) …
System Xc −/GSH/GPX4 axis: An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy
FJ Li, HZ Long, ZW Zhou, HY Luo, SG Xu… - Frontiers in …, 2022 - frontiersin.org
The activation of ferroptosis is a new effective way to treat drug-resistant solid tumors.
Ferroptosis is an iron-mediated form of cell death caused by the accumulation of lipid …
Ferroptosis is an iron-mediated form of cell death caused by the accumulation of lipid …
Ferroptosis, a novel pharmacological mechanism of anti-cancer drugs
Y Su, B Zhao, L Zhou, Z Zhang, Y Shen, H Lv… - Cancer letters, 2020 - Elsevier
Ferroptosis, a form of regulated cell death, is initiated by oxidative perturbations of the
intracellular microenvironment, which is under the constitutive control of glutathione …
intracellular microenvironment, which is under the constitutive control of glutathione …
Ferroptosis and cancer: mitochondria meet the “iron maiden” cell death
Ferroptosis is a new type of oxidative regulated cell death (RCD) driven by iron-dependent
lipid peroxidation. As major sites of iron utilization and master regulators of oxidative …
lipid peroxidation. As major sites of iron utilization and master regulators of oxidative …
Reactive oxygen species (ROS) regulates different types of cell death by acting as a rheostat
GE Villalpando-Rodriguez… - Oxidative Medicine and …, 2021 - Wiley Online Library
Reactive oxygen species (ROS) are essential for cellular signaling and response to stress.
The level of ROS and the type of ROS determine the ability of cells to undergo cell death …
The level of ROS and the type of ROS determine the ability of cells to undergo cell death …
Molecular mechanisms of ferroptosis and its role in cancer therapy
T Xu, W Ding, X Ji, X Ao, Y Liu, W Yu… - Journal of cellular and …, 2019 - Wiley Online Library
Ferroptosis is a newly defined programmed cell death process with the hallmark of the
accumulation of iron‐dependent lipid peroxides. The term was first coined in 2012 by the …
accumulation of iron‐dependent lipid peroxides. The term was first coined in 2012 by the …
Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis
R Wen, X Dong, H Zhuang, F Pang, S Ding, N Li, Y Mai… - Phytomedicine, 2023 - Elsevier
Background Osteosarcomas (OS) is a kind of malignant bone tumor which occurs primarily
in children and adolescents, and the clinical therapeutics remain disappointing. As a new …
in children and adolescents, and the clinical therapeutics remain disappointing. As a new …
The application of ferroptosis in diseases
Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …
LncRNA HEPFAL accelerates ferroptosis in hepatocellular carcinoma by regulating SLC7A11 ubiquitination
B Zhang, W Bao, S Zhang, B Chen, X Zhou… - Cell death & …, 2022 - nature.com
Ferroptosis is a new type of cell death that has been recognized in recent years and is
different from apoptosis, autophagy, and necrosis. It is mainly due to cellular iron …
different from apoptosis, autophagy, and necrosis. It is mainly due to cellular iron …