Biological applications of knowledge graph embedding models
SK Mohamed, A Nounu, V Nováček - Briefings in bioinformatics, 2021 - academic.oup.com
Complex biological systems are traditionally modelled as graphs of interconnected
biological entities. These graphs, ie biological knowledge graphs, are then processed using …
biological entities. These graphs, ie biological knowledge graphs, are then processed using …
On the integration of knowledge graphs into deep learning models for a more comprehensible AI—Three challenges for future research
G Futia, A Vetrò - Information, 2020 - mdpi.com
Deep learning models contributed to reaching unprecedented results in prediction and
classification tasks of Artificial Intelligence (AI) systems. However, alongside this notable …
classification tasks of Artificial Intelligence (AI) systems. However, alongside this notable …
[HTML][HTML] Clinical evaluation of atlas and deep learning based automatic contouring for lung cancer
T Lustberg, J van Soest, M Gooding… - Radiotherapy and …, 2018 - Elsevier
Background and purpose Contouring of organs at risk (OARs) is an important but time
consuming part of radiotherapy treatment planning. The aim of this study was to investigate …
consuming part of radiotherapy treatment planning. The aim of this study was to investigate …
Discovering protein drug targets using knowledge graph embeddings
SK Mohamed, V Nováček, A Nounu - Bioinformatics, 2020 - academic.oup.com
Motivation Computational approaches for predicting drug–target interactions (DTIs) can
provide valuable insights into the drug mechanism of action. DTI predictions can help to …
provide valuable insights into the drug mechanism of action. DTI predictions can help to …
Complex query answering with neural link predictors
Neural link predictors are immensely useful for identifying missing edges in large scale
Knowledge Graphs. However, it is still not clear how to use these models for answering …
Knowledge Graphs. However, it is still not clear how to use these models for answering …
The Monarch Initiative: an integrative data and analytic platform connecting phenotypes to genotypes across species
The correlation of phenotypic outcomes with genetic variation and environmental factors is a
core pursuit in biology and biomedicine. Numerous challenges impede our progress: patient …
core pursuit in biology and biomedicine. Numerous challenges impede our progress: patient …
SMR: medical knowledge graph embedding for safe medicine recommendation
Most of the existing medicine recommendation systems that are mainly based on electronic
medical records (EMRs) are significantly assisting doctors to make better clinical decisions …
medical records (EMRs) are significantly assisting doctors to make better clinical decisions …
[HTML][HTML] The role of metadata in reproducible computational research
Reproducible computational research (RCR) is the keystone of the scientific method for in
silico analyses, packaging the transformation of raw data to published results. In addition to …
silico analyses, packaging the transformation of raw data to published results. In addition to …
RTX-KG2: a system for building a semantically standardized knowledge graph for translational biomedicine
Background Biomedical translational science is increasingly using computational reasoning
on repositories of structured knowledge (such as UMLS, SemMedDB, ChEMBL, Reactome …
on repositories of structured knowledge (such as UMLS, SemMedDB, ChEMBL, Reactome …
OpenBioLink: a benchmarking framework for large-scale biomedical link prediction
Recently, novel machine-learning algorithms have shown potential for predicting
undiscovered links in biomedical knowledge networks. However, dedicated benchmarks for …
undiscovered links in biomedical knowledge networks. However, dedicated benchmarks for …