Molecular mechanisms for bacterial potassium homeostasis

J Stautz, Y Hellmich, MF Fuss, JM Silberberg… - Journal of molecular …, 2021 - Elsevier
Potassium ion homeostasis is essential for bacterial survival, playing roles in
osmoregulation, pH homeostasis, regulation of protein synthesis, enzyme activation …

Two component regulatory systems and antibiotic resistance in Gram-negative pathogens

AY Bhagirath, Y Li, R Patidar, K Yerex, X Ma… - International journal of …, 2019 - mdpi.com
Gram-negative pathogens such as Klebsiella pneumoniae, Acinetobacter baumannii, and
Pseudomonas aeruginosa are the leading cause of nosocomial infections throughout the …

Beyond homeostasis: Potassium and pathogenesis during bacterial infections

EA Do, CM Gries - Infection and immunity, 2021 - Am Soc Microbiol
Potassium is an essential mineral nutrient required by all living cells for normal physiological
function. Therefore, maintaining intracellular potassium homeostasis during bacterial …

A c-di-AMP riboswitch controlling kdpFABC operon transcription regulates the potassium transporter system in Bacillus thuringiensis

X Wang, X Cai, H Ma, W Yin, L Zhu, X Li… - Communications …, 2019 - nature.com
The intracellular K+ level in bacteria is strictly controlled by K+ uptake and efflux systems.
Among these, KdpFABC is a high-affinity K+ transporter system that is generally activated by …

Regulation of Inducible Potassium Transporter KdpFABC by the KdpD/KdpE Two-Component System in Mycobacterium smegmatis

MK Ali, X Li, Q Tang, X Liu, F Chen, J Xiao… - Frontiers in …, 2017 - frontiersin.org
Kdp-ATPase is an inducible high affinity potassium uptake system that is widely distributed
in bacteria, and is generally regulated by the KdpD/KdpE two-component system (TCS). In …

Response regulator KdpE contributes to Aeromonas dhakensis virulence

L Chen, Y Wang, L Fan, N Yang, J Zeng, G Guo, Q Li… - Aquaculture, 2023 - Elsevier
Aeromonas dhakensis is an emerging pathogen that is harmful to humans and aquaculture
in tropical areas. The aim of this study was to understand the role of the two-component …

Carbapenem-resistant Acinetobacter baumannii (CRAB): metabolic adaptation and transcriptional response to human urine (HU)

J Escalante, M Hamza, B Nishimura, M Melecio… - Scientific Reports, 2024 - nature.com
Carbapenem-resistant Acinetobacter baumannii (CRAB) is a major human pathogen and a
research priority for developing new antimicrobial agents. CRAB is a causative agent of a …

Independent component analysis reveals 49 independently modulated gene sets within the global transcriptional regulatory architecture of multidrug-resistant …

ND Menon, S Poudel, AV Sastry, K Rychel, R Szubin… - Msystems, 2024 - Am Soc Microbiol
Acinetobacter baumannii causes severe infections in humans, resists multiple antibiotics,
and survives in stressful environmental conditions due to modulations of its complex …

[HTML][HTML] Potential genes associated with survival of Acinetobacter baumannii under ciprofloxacin stress

S Kashyap, P Sharma, N Capalash - Microbes and Infection, 2021 - Elsevier
Acinetobacter baumannii is an opportunistic pathogen that has acquired resistance to all
available drugs. The rise in multi-drug resistance in A. baumannii has been exacerbated by …

K+ homeostasis is important for survival of Acinetobacter baumannii ATCC 19606 in the nosocomial environment

P König, B Averhoff, V Müller - International Microbiology, 2024 - Springer
Pathogenic bacteria have developed several mechanisms to thrive within the hostile
environment of the human host, but it is often disregarded that their survival outside this …