Acridine‐1, 8‐diones: Synthesis and Biological Applications

N Sahiba, A Sethiya, J Soni, S Agarwal - ChemistrySelect, 2021 - Wiley Online Library
The unpretentious features of acridine‐1, 8‐diones viz. presence of N‐heteroatom,
electronic behavior, acridine ring skeleton and wide possibilities of diversified substitution …

1, 4-Dihydropyridine Derivatives: An Overview of Synthesis Conditions and Biological Tests

A de Fátima Silva Lago… - Current Organic …, 2023 - ingentaconnect.com
1, 4-dihydropyridine is a versatile class of compounds with multiple biological activities, thus
holding significant pharmacological potential. Recent studies have provided evidence …

Green and efficient synthesis of acridine-1,8-diones and hexahydroquinolines via a KH2PO4 catalyzed Hantzsch-type reaction in aqueous ethanol

SJ Yü, S Wu, XM Zhao, CW Lü - Research on Chemical Intermediates, 2017 - Springer
A simple, clean, and economical methodology for the synthesis of acridine-1, 8-dione and
hexahydroquinoline derivatives via Hantzsch-type condensation has been described. This …

[PDF][PDF] Crystal structure and Hirshfeld surface analysis of 6-amino-8-(2, 6-dichlorophenyl)-1, 3, 4, 8-tetrahydro-2H-pyrido [1, 2-a] pyrimidine-7, 9-dicarbonitrile

FN Naghiyev, TA Tereshina, VN Khrustalev… - Acta …, 2021 - journals.iucr.org
In the molecular structure of the title compound, C16H13Cl2N5, the 1, 4-dihydropyridine ring
of the 1, 3, 4, 8-tetrahydro-2H-pyrido [1, 2-a] pyrimidine ring system adopts a screw-boat …

[PDF][PDF] Crystal structure and Hirshfeld surface analysis of 1-(2-amino-4-methyl-1, 3-thiazol-5-yl) ethan-1-one

EZ Huseynov, M Akkurt, I Brito, A Bhattarai… - Acta …, 2023 - journals.iucr.org
In the title compound, C6H8N2OS, all atoms except for the methyl H atoms are coplanar,
with a maximum deviation of 0.026 (4) Å. In the crystal, pairs of molecules are linked by N …

[HTML][HTML] Aqua-mediated synthesis of acridinediones with reusable silica-supported sulfuric acid as an efficient catalyst

SS Mansoor, K Aswin, K Logaiya… - Journal of Taibah …, 2014 - Elsevier
A simple approach to the synthesis of acridinediones via one-pot three-component
condensation of an aromatic aldehyde, 5, 5-dimethyl-1, 3-cyclohexanedione (dimedone) …

β-Enaminones from cyclohexane-1,3-diones: Versatile precursors for nitrogen and oxygen-containing heterocycles synthesis

D Sharma, M Kumar, S Kumar… - Synthetic …, 2023 - Taylor & Francis
Abstract β-Enaminones derived from cyclohexane-1, 3-diones reveal a vast variety of
bioactivities including anticonvulsant, anti-inflammatory, analgesic, etc. Further, these β …

Applications of dimedone in the synthesis of heterocycles: an update

M M. Heravi, V Zadsirjan, B Fattahi… - Current Organic …, 2016 - benthamdirect.com
Dimedone (5, 5-dimethylcyclohexane-1, 3-dione) is an alicyclic diketone, occasionally
considered as building blocks in design and synthesis of a wide variety of heterocycles. The …

One‐pot cascade synthesis and in vitro evaluation of anti‐inflammatory and antidiabetic activities of S‐methylphenyl substituted acridine‐1, 8‐diones

L Mallu, D Thirumalai… - Chemical Biology & Drug …, 2017 - Wiley Online Library
Various S‐methylphenyl substituted acridine‐1, 8‐dione series (4a–i) were synthesized
through a one‐pot cascade synthetic approach involving the reaction of 4‐(methylthio) …

Uses of cyclohexan‐1,3‐dione for the synthesis of tetrahydrochromeno[3,4‐c]chromen derivatives with anti‐tumor activities

RM Mohareb, NY Megally Abdo… - Journal of Heterocyclic …, 2020 - Wiley Online Library
Abstract Cyclohexan‐1, 3‐dione (1) was used as the key starting material, which reacted
with salicylaldehyde (2) and either malononitrile (3a) or ethyl cyanoacetate (3b) in ethanol …