Cytochrome c oxidase (CcO) is the terminal oxidase of the mitochondrial electron transport
chain. This bigenomic enzyme in mammals contains 13 subunits of which the 3 catalytic …

Abstract The generation of Reactive Oxygen Species (ROS) as by‐products in mitochondria
Electron Transport Chain (ETC) has long been admitted as the cost of aerobic energy …

The inefficiency of cyanide/HCN (CN) binding with heme proteins (under physiological
regimes) is demonstrated with an assessment of thermodynamics, kinetics, and inhibition …

Mitochondria maintain cellular homeostasis by coordinating ATP synthesis with metabolic
activity, redox signaling, and apoptosis. Excessive levels of mitochondria-derived reactive …

Cytochrome c-dependent electron transfer and apoptosome activation require protein−
protein binding, which are mainly directed by conformational and specific electrostatic …

Chronic treatment of cultured cells with very low levels of azide (I 50< 10 μm) leads to slow (t
½= 6 h), irreversible loss of cytochrome c oxidase (COX) activity. Azide-mediated COX …

The mechanism of antimalarial activity of clotrimazole was studied placing emphasis on its
role in inhibiting hemoperoxidase for inducing oxidative stress in Plasmodium falciparum …

Reaction between nitrogen‐centered radicals and unsaturated C− C bonds is an effective
synthetic strategy for the construction of nitrogen‐containing molecules. Although the …

Впервые произведены посевы микроорганизмов на культуральные среды, содержащие
белый фосфор в качестве единственного источника фосфора. На данных средах …

We show here the first radical route for the direct photosynthesis of AuCN oligomers with
different sizes and shapes, as evidenced by TEM observations, from an Au nanoparticle …