Marine natural products

AR Carroll, BR Copp, RA Davis, RA Keyzers… - Natural product …, 2021 - pubs.rsc.org
This review covers the literature published in 2019 for marine natural products (MNPs), with
719 citations (701 for the period January to December 2019) referring to compounds …

A critical review on the use of DP4+ in the structural elucidation of natural products: the good, the bad and the ugly. A practical guide

MO Marcarino, S Cicetti, MM Zanardi… - Natural Product …, 2022 - pubs.rsc.org
Covering: 2015 up to the end of 2020 Even in the golden age of NMR, the number of natural
products being incorrectly assigned is becoming larger every day. The use of quantum NMR …

NMR calculations with quantum methods: development of new tools for structural elucidation and beyond

MO Marcarino, MM Zanardi, S Cicetti… - Accounts of Chemical …, 2020 - ACS Publications
Conspectus Structural elucidation is an important and challenging stage in the discovery of
new organic molecules. Single-crystal X-ray analysis provides the most unquestionable …

Sensitivity analysis of DP4+ with the probability distribution terms: Development of a universal and customizable method

MM Zanardi, AM Sarotti - The Journal of Organic Chemistry, 2021 - ACS Publications
DP4+ is a popular tool for structural elucidation using GIAO NMR calculations. The method
was built with 16 statistical parameters [μ, σ, ν], which depend on the level of theory. Herein …

Computer assisted structure elucidation (CASE): current and future perspectives

M Elyashberg, D Argyropoulos - Magnetic Resonance in …, 2021 - Wiley Online Library
The first efforts for the development of methods for Computer‐Assisted Structure Elucidation
(CASE) were published more than 50 years ago. CASE expert systems based on one …

Trends of antimalarial marine natural products: Progresses, challenges and opportunities

Y Hai, ZM Cai, PJ Li, MY Wei, CY Wang, YC Gu… - Natural Product …, 2022 - pubs.rsc.org
Covering 1972 to 2021 Malaria remains a significant public health problem in some regions
of the world. The great efforts to control malaria have been severely compromised due to the …

Chemical synthesis of oligosaccharides and their application in new drug research

Z Lv, H Liu, H Hao, FU Rahman, Y Zhang - European Journal of Medicinal …, 2023 - Elsevier
Oligosaccharides are the ubiquitous molecules of life. In order to translate human
bioglycosylation into clinical applications, homogeneous samples of oligosaccharides and …

Marine natural products as leads against SARS-CoV-2 infection

BK Chhetri, PR Tedbury… - Journal of natural …, 2022 - ACS Publications
Since early 2020, disease caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has become a global pandemic, causing millions of infections and deaths …

Antibiotics development and the potentials of marine-derived compounds to stem the tide of multidrug-resistant pathogenic bacteria, fungi, and protozoa

JA Nweze, FN Mbaoji, G Huang, Y Li, L Yang, Y Zhang… - Marine Drugs, 2020 - mdpi.com
As the search for new antibiotics continues, the resistance to known antimicrobial
compounds continues to increase. Many researchers around the world, in response to …

Catalysis-Enabled 13-Step Total Synthesis of (−)-Peyssonnoside A

B Xu, C Liu, M Dai - Journal of the American Chemical Society, 2022 - ACS Publications
We report a 13-step enantioselective and stereoselective total synthesis of (−)-
peyssonnoside A, a unique diterpene glucoside with a rare and highly congested …