Modeling the extracellular matrix in cell migration and morphogenesis: a guide for the curious biologist

RM Crossley, S Johnson, E Tsingos, Z Bell… - Frontiers in cell and …, 2024 - frontiersin.org
The extracellular matrix (ECM) is a highly complex structure through which biochemical and
mechanical signals are transmitted. In processes of cell migration, the ECM also acts as a …

Analysis on block chain financial transaction under artificial neural network of deep learning

W Gao, C Su - Journal of Computational and Applied Mathematics, 2020 - Elsevier
In order to conduct an in-depth study on financial transactions of block chain, the classical
back propagation (BP) neural network based on the artificial neural network (ANN) model is …

Multiscale model of the different modes of cancer cell invasion

M Ruscone, A Montagud, P Chavrier, O Destaing… - …, 2023 - academic.oup.com
Motivation Mathematical models of biological processes altered in cancer are built using the
knowledge of complex networks of signaling pathways, detailing the molecular regulations …

Biological multiscale computational modeling: A promising tool for 3D bioprinting and tissue engineering

BC dos Santos, PY Noritomi, JVL da Silva, IA Maia… - Bioprinting, 2022 - Elsevier
The progress of three-dimensional (3D) bioprinting techniques has driven several advances
in tissue engineering (TE), which allow the obtention of biological constructs analogous to …

Evolutionary computational platform for the automatic discovery of nanocarriers for cancer treatment

NR Stillman, I Balaz, MA Tsompanas… - NPJ Computational …, 2021 - nature.com
We present the EVONANO platform for the evolution of nanomedicines with application to
anti-cancer treatments. Our work aims to decrease both the time and cost required to …

PhysiBoSS 2.0: a sustainable integration of stochastic Boolean and agent-based modelling frameworks

M Ponce-de-Leon, A Montagud, V Noël… - npj Systems Biology …, 2023 - nature.com
In systems biology, mathematical models and simulations play a crucial role in
understanding complex biological systems. Different modelling frameworks are employed …

[图书][B] Mathematical models of cancer and different therapies

Accurate and reliable model representations of cancer dynamics are milestones in the field
of cancer research. Mathematical modeling approaches are abundantly used in cancer …

Novel ground-up 3D multicellular simulators for synthetic biology CAD integrating stochastic Gillespie simulations benchmarked with topologically variable SBML …

RO Matzko, L Mierla, S Konur - Genes, 2023 - mdpi.com
The elevation of Synthetic Biology from single cells to multicellular simulations would be a
significant scale-up. The spatiotemporal behavior of cellular populations has the potential to …

An effective surrogate model assisted algorithm for multi-objective optimization: application to wind farm layout design

Y Chen, L Wang, H Huang - Frontiers in Energy Research, 2023 - frontiersin.org
Due to the intricate and diverse nature of industrial systems, traditional optimization
algorithms require a significant amount of time to search for the optimal solution throughout …

[HTML][HTML] In silico optimization of cancer therapies with multiple types of nanoparticles applied at different times

MA Tsompanas, L Bull, A Adamatzky, I Balaz - Computer Methods and …, 2021 - Elsevier
Abstract Background and Objective: Cancer tumors constitute a complicated environment for
conventional anti-cancer treatments to confront, so solutions with higher complexity and …