Molecular tools for facilitative carbohydrate transporters (Gluts)

M Tanasova, JR Fedie - ChemBioChem, 2017 - Wiley Online Library
Facilitative carbohydrate transporters—Gluts—have received wide attention over decades
due to their essential role in nutrient uptake and links with various metabolic disorders …

On the track to the beta-cell

WJ Malaisse - Diabetologia, 2001 - Springer
The imaging and quantification of the endocrine pancreas by a non-invasive procedure
remains a challenge. In the prolongation of prior work on selected succinic acid esters and …

6-Fluoro-6-deoxy-d-glucose as a tracer of glucose transport

BR Landau, CL Spring-Robinson… - American Journal …, 2007 - journals.physiology.org
Glucose transport rates are estimated noninvasively in physiological and pathological states
by kinetic imaging using PET. The glucose analog most often used is 18F-labeled 2FDG …

Carbohydrate‐based molecules for molecular imaging in nuclear medicine

G Ribeiro Morais, RA Falconer… - European Journal of …, 2013 - Wiley Online Library
This review covers published literature describing the synthesis of labeled carbohydrates for
use in molecular imaging, with a particular focus on the use of nuclear techniques (PET …

Labeled glucose analogs in the genomic era

SJ Gatley - Journal of Nuclear Medicine, 2003 - Soc Nuclear Med
Medicine, Bormans et al.(1) examine the uptake of 11C-labeled D-glucose analogs α-methyl-
D-glucoside and β-methyl-D-glucoside in the mouse kidney. It appears that both of these …

Assessment of insulin resistance in fructose-fed rats with 125I-6-deoxy-6-iodo-D-glucose, a new tracer of glucose transport

P Perret, L Slimani, A Briat, D Villemain… - European journal of …, 2007 - Springer
Purpose Insulin resistance, characterised by an insulin-stimulated glucose transport defect,
is an important feature of the pre-diabetic state that has been observed in numerous …

Synthesis of [18F]‐6‐deoxy‐6‐fluoro‐D‐glucose ([18F]6FDG), a potential tracer of glucose transport

TR Neal, WC Schumann, MS Berridge… - Journal of Labelled …, 2005 - Wiley Online Library
With the goal of developing a PET radioligand for the in vivo assessment of glucose
transport, 6‐deoxy‐6‐[18F] fluoro‐d‐glucose ([18F] 6FDG) was prepared in two steps from …

Radiographic assessment of tissue after exposure to a compound

J Salb - US Patent 6,751,290, 2004 - Google Patents
(65) Prior Publication Data (57) ABSTRACT US 2002/0039401A1 Apr. 4, 2002 Radiographic
System and method for noninvasively assess Related US Application Data ing the response …

Assessment of insulin sensitivity in vivo in control and diabetic mice with a radioactive tracer of glucose transport: [125I]‐6‐deoxy‐6‐iodo‐D‐glucose

P Perret, C Ghezzi, JP Mathieu… - … research and reviews, 2003 - Wiley Online Library
Background Impairment of insulin‐stimulated glucose transport is a characteristic of type 2
diabetes. A radioactive glucose analogue has been synthesized:[125I]‐6‐deoxy‐6‐iodo‐d …

Amino acids influence the glucose uptake through GLUT4 in CHO-K1 cells under high glucose conditions

R Selvi, N Angayarkanni, B Asma… - Molecular and cellular …, 2010 - Springer
According to studies earlier, amino acids have proven to be antidiabetic, antiglycating, and
anticataractogenic. The present study was to explore whether amino acids as mixtures could …