The hitchhiker's guide to flow chemistry∥
Flow chemistry involves the use of channels or tubing to conduct a reaction in a continuous
stream rather than in a flask. Flow equipment provides chemists with unique control over …
stream rather than in a flask. Flow equipment provides chemists with unique control over …
Emerging trends in flow chemistry and applications to the pharmaceutical industry
AR Bogdan, AW Dombrowski - Journal of medicinal chemistry, 2019 - ACS Publications
The field of flow chemistry has garnered considerable attention over the past 2 decades.
This Perspective highlights many recent advances in the field of flow chemistry and …
This Perspective highlights many recent advances in the field of flow chemistry and …
A perspective on continuous flow chemistry in the pharmaceutical industry
M Baumann, TS Moody, M Smyth… - … Process Research & …, 2020 - ACS Publications
Continuous flow manufacture is an innovative technology platform, which is gaining
momentum within the pharmaceutical industry. The key advantages of continuous flow …
momentum within the pharmaceutical industry. The key advantages of continuous flow …
Continuous flow chemistry: where are we now? Recent applications, challenges and limitations
FM Akwi, P Watts - Chemical communications, 2018 - pubs.rsc.org
A general outlook of the changing face of chemical synthesis is provided in this article
through recent applications of continuous flow processing in both industry and academia …
through recent applications of continuous flow processing in both industry and academia …
A Lewis base catalysis approach for the photoredox activation of boronic acids and esters
We report herein the use of a dual catalytic system comprising a Lewis base catalyst such as
quinuclidin‐3‐ol or 4‐dimethylaminopyridine and a photoredox catalyst to generate carbon …
quinuclidin‐3‐ol or 4‐dimethylaminopyridine and a photoredox catalyst to generate carbon …
The evolving state of continuous processing in pharmaceutical API manufacturing: a survey of pharmaceutical companies and contract manufacturing organizations
JC McWilliams, AD Allian, SM Opalka… - … Process Research & …, 2018 - ACS Publications
This manuscript provides the results of an in-depth survey assessment of the capabilities,
experience, and perspectives on continuous processing in the pharmaceutical sector, with …
experience, and perspectives on continuous processing in the pharmaceutical sector, with …
Forgotten and forbidden chemical reactions revitalised through continuous flow technology
A Bonner, A Loftus, AC Padgham… - Organic & Biomolecular …, 2021 - pubs.rsc.org
Continuous flow technology has played an undeniable role in enabling modern chemical
synthesis, whereby a myriad of reactions can now be performed with greater efficiency …
synthesis, whereby a myriad of reactions can now be performed with greater efficiency …
Flow microreactor technology for taming highly reactive chloroiodomethyllithium carbenoid: Direct and chemoselective synthesis of α-chloroaldehydes
A straightforward flow synthesis of α-chloro aldehydes has been developed. The strategy
involves, for the first time, the thermal unstable chloroiodomethyllithium carbenoid and …
involves, for the first time, the thermal unstable chloroiodomethyllithium carbenoid and …
Flow chemistry in contemporary chemical sciences: A real variety of its applications
M Trojanowicz - Molecules, 2020 - mdpi.com
Flow chemistry is an area of contemporary chemistry exploiting the hydrodynamic conditions
of flowing liquids to provide particular environments for chemical reactions. These particular …
of flowing liquids to provide particular environments for chemical reactions. These particular …
External flash generation of carbenoids enables monodeuteration of dihalomethanes
K Okamoto, R Higuma, K Muta… - … A European Journal, 2023 - Wiley Online Library
In this study, incorporation of one deuterium atom was achieved by H− D exchange of one of
the two identical methylene protons in various dihalomethanes (halogen= Cl, Br, and I) …
the two identical methylene protons in various dihalomethanes (halogen= Cl, Br, and I) …