Clinical considerations for medication-related osteonecrosis of the jaw: a comprehensive literature review
M Kawahara, S Kuroshima, T Sawase - International journal of implant …, 2021 - Springer
Background Medication-related osteonecrosis of the jaw (MRONJ), which was first reported
as bisphosphonate-related osteonecrosis of the jaw (BRONJ) in bisphosphonate users, is a …
as bisphosphonate-related osteonecrosis of the jaw (BRONJ) in bisphosphonate users, is a …
Preclinical models of medication-related osteonecrosis of the jaw (MRONJ)
JI Aguirre, EJ Castillo, DB Kimmel - Bone, 2021 - Elsevier
Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe adverse event
affecting patients with cancer and patients with osteoporosis who have been treated with …
affecting patients with cancer and patients with osteoporosis who have been treated with …
Medication‐related osteonecrosis of the jaw: a literature review and update
S Kuroshima, FA Al‐Omari, M Sasaki, T Sawase - Genesis, 2022 - Wiley Online Library
Since the initial description of medication‐related osteonecrosis of the jaw (MRONJ) almost
two decades ago, the potential pathophysiology and risk factors have been elaborated on in …
two decades ago, the potential pathophysiology and risk factors have been elaborated on in …
Osteonecrosis development by tooth extraction in zoledronate treated mice is inhibited by active vitamin D analogues, anti-inflammatory agents or antibiotics
T Soma, R Iwasaki, Y Sato, T Kobayashi, E Ito… - Scientific reports, 2022 - nature.com
Invasive dental treatment such as tooth extraction following treatment with strong anti-bone
resorptive agents, including bisphosphonates and denosumab, reportedly promotes …
resorptive agents, including bisphosphonates and denosumab, reportedly promotes …
Risk factors for bisphosphonate-associated osteonecrosis of the jaw in the prospective randomized trial of adjuvant bisphosphonates for early-stage breast cancer …
DA Kizub, J Miao, MM Schubert, AHG Paterson… - Supportive Care in …, 2021 - Springer
Purpose Bisphosphonates reduce bone metastases in postmenopausal women with early-
stage breast cancer but carry the risk of bisphosphonate-related osteonecrosis of the jaw …
stage breast cancer but carry the risk of bisphosphonate-related osteonecrosis of the jaw …
Depletion of macrophages deteriorates bisphosphonate-related osteonecrosis of the jaw-like lesions in mice
R Kozutsumi, S Kuroshima, FA Al-Omari, H Hayano… - Bone, 2023 - Elsevier
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a potentially intractable
disease with no definitive pathophysiology and no treatment and prevention strategies. This …
disease with no definitive pathophysiology and no treatment and prevention strategies. This …
Rodents as an animal model for studying tooth extraction-related medication-related osteonecrosis of the jaw: assessment of outcomes
Objective To assess the outcomes of several rodent animal models for studying tooth
extraction-related medication-related osteonecrosis of the jaw (MRONJ). Design After a …
extraction-related medication-related osteonecrosis of the jaw (MRONJ). Design After a …
BMP-2/β-TCP local delivery for bone regeneration in MRONJ-like mouse model
A Mikai, M Ono, I Tosa, HTT Nguyen, ES Hara… - International journal of …, 2020 - mdpi.com
Medication-related osteonecrosis of the jaw (MRONJ) is a severe pathological condition
associated mainly with the long-term administration of bone resorption inhibitors, which are …
associated mainly with the long-term administration of bone resorption inhibitors, which are …
Dynamic polarization shifting from M1 to M2 macrophages in reduced osteonecrosis of the jaw-like lesions by cessation of anti-RANKL antibody in mice
S Tamaki, S Kuroshima, H Hayano, K Nakajima… - Bone, 2020 - Elsevier
Denosumab-related osteonecrosis of the jaw (DRONJ), which mainly occurs in cancer
patients receiving anti-receptor activator NF-kappaB ligand (RANKL) antibody, reduces oral …
patients receiving anti-receptor activator NF-kappaB ligand (RANKL) antibody, reduces oral …
Establishment and assessment of rodent models of medication-related osteonecrosis of the jaw (MRONJ)
R Yan, R Jiang, L Hu, Y Deng, J Wen… - International journal of …, 2022 - nature.com
Medication-related osteonecrosis of the jaw (MRONJ) is primarily associated with
administering antiresorptive or antiangiogenic drugs. Despite significant research on …
administering antiresorptive or antiangiogenic drugs. Despite significant research on …