Towards translational optogenetics

A Bansal, S Shikha, Y Zhang - Nature Biomedical Engineering, 2023 - nature.com
Optogenetics is widely used to interrogate the neural circuits underlying disease and has
most recently been harnessed for therapeutic applications. The optogenetic toolkit consists …

Specificity, versatility, and continual development: the power of optogenetics for epilepsy research

Z Christenson Wick, E Krook-Magnuson - Frontiers in cellular …, 2018 - frontiersin.org
Optogenetics is a powerful and rapidly expanding set of techniques that use genetically
encoded light sensitive proteins such as opsins. Through the selective expression of these …

Functional ultrasound imaging of the spreading activity following optogenetic stimulation of the rat visual cortex

M Provansal, G Labernède, C Joffrois, A Rizkallah… - Scientific reports, 2021 - nature.com
Optogenetics has revolutionized neurosciences by allowing fine control of neuronal activity.
An important aspect for this control is assessing the activation and/or adjusting the …

[HTML][HTML] Optogenetics for neural transplant manipulation and functional analysis

R Habibey, K Sharma, A Swiersy… - … and Biophysical Research …, 2020 - Elsevier
Transplantation of neural stem cells (NSCs) or NSC-derived neurons into the brain is a
promising therapeutic approach to restore neuronal function. Rapid progress in the NSCs …

Optogenetic control of human stem cell-derived neurons

R Habibey, J Striebel, K Sharma… - Rhodopsin: Methods and …, 2022 - Springer
Spontaneous and optogenetically evoked activities of human induced pluripotent stem cell
(hiPSC)-derived neurons can be assessed by patch clamp and multi-electrode array (MEA) …

Imaging of Stem Cell Therapy for Stroke and Beyond

B Nowak, A Andrzejewska, P Rogujski… - … Therapies in Ischemic …, 2022 - Springer
Stem cell-based regenerative medicine is an attractive approach for the treatment of
neurological diseases such as ischemic stroke. Preclinical studies have shown that …

Intracellularly targeted optogenetic actuators

J Wang, BM Kampa, A Offenhäusser - 2023 - publications.rwth-aachen.de
Die Optogenetik entwickelte sich in den letzten Jahren zu einer leistungsstarken Technik,
die optische und genetische Methoden kombiniert, um die Zellaktivität zu überwachen und …

Optogenetics in Stem Cell Research: Focus on the Central Nervous System

J Boltze, A Stroh - Optogenetics: A Roadmap, 2018 - Springer
Stem cell-based therapies of CNS disorders represent a promising approach in translational
and regenerative medicine. Stem cell-based tissue replacement and regeneration would, for …

Electronic devices for the combination of electrically controlled drug release, electrostimulation, and optogenetic stimulation for nerve tissue regeneration

J Monreal Trigo - 2023 - riunet.upv.es
[EN] The stem cells' ability to proliferate to form different specialized cells gives them the
potential to serve as the basis for effective therapies for pathologies whose treatment was …

[PDF][PDF] Electronic devices for the combination of electrically controlled drug release, electrostimulation, and optogenetic stimulation for nerve tissue regeneration

JM Trigo, RM Máñez - 2023 - researchgate.net
Since the dawn of medicine, the regeneration of central nervous system injuries has inspired
myths and legends. People without the ability to walk due to spinal cord injury could walk …