FBXW7 (also known as Fbw7, Sel10, hCDC4, or hAgo) is a tumor suppressor and the most
frequently mutated member of the F-box protein family in human cancers. FBXW7 functions …

Breast cancer is one of the frequent tumors that seriously endanger the physical and mental
well-being in women. F-box and WD repeat domain-containing 7 (FBXW7) is a neoplastic …

Arginine methylation is an important posttranslational modification catalyzed by protein
arginine methyltransferases (PRMTs). However, the role of PRMTs in colorectal cancer …

The non‐POU domain‐containing octamer‐binding protein NONO/p54nrb, which belongs to
the Drosophila behaviour/human splicing (DBHS) family, is a multifunctional nuclear protein …

The F-Box and WD Repeat Domain Containing 7 (FBXW7) protein has been shown to
regulate cellular growth and act as a tumor suppressor. This protein, also known as FBW7 …

BRAF inhibitors (BRAFi) that target BRAF V600E kinase, a driver mutation found in 50% of
melanomas, show a significant antitumor response, but the common emergence of acquired …

Gallbladder carcinoma (GBC) is the most aggressive carcinoma of the biliary tract, effective
chemotherapy was critical for the patients with unresectable GBC. However, chemotherapy …

TFE3 gene fusions often place TFE3 under the control of a more active promoter and cause
overexpression of the TFE3 proteins in renal cell carcinoma associated with Xp11. 2 …

Background Long non-coding RNA (lncRNA) plays a vital role in the occurrence and
development of varieties of tumors. Previous studies have shown that lncRNA GClnc1 is …

Abstract Ubiquitin‐specific protease 11 (USP11) has been implicated in the regulation of
DNA repair, apoptosis, signal transduction and cell cycle. It belongs to a USP subfamily of …