Intraspinal Drug Delivery Methods and Devices To Alleviate Chronic Pelvic Pain

K Hildebrand - US Patent App. 11/380,814, 2007 - Google Patents
The disclosure describes methods and systems for alleviat ing chronic pelvic pain in a
Subject by intraspinally a therapeutically effective amount of a chronic pelvic pain alleviating …

Bupivacaine formulation in a polyorthoester carrier

CM Hobot, ME Benz, KR Hildebrand… - US Patent 8,956,642, 2015 - Google Patents
(56) References Cited(57) ABSTRACT US PATENT DOCUMENTS Effective treatments of
pain, such as chronic pelvic pain, for 2.957. 856. A 10, 1960 G 1 extended periods of time …

Pharmaceutical removal of neuronal extensions from a degenerating disc

J Roy, SJ Drapeau, JC Marx - US Patent 8,916,611, 2014 - Google Patents
In one aspect of the invention, a method for treating disco genic pain is provided that
includes administering an effec tive amount of a therapeutic agent to a disc, in which the …

Pharmaceutical removal of vascular and/or neuronal extensions form a degenerating disc

J Roy, S Drapeau, J Marx - US Patent App. 11/414,689, 2007 - Google Patents
The invention provides a method for alleviating discogenic pain by administering a
therapeutic agent that disrupts neuronal and/or vascular elements in the disc, which is …

Pharmaceutical removal of neuronal extensions from a degenerating disc

J Roy, SJ Drapeau, JC Marx - US Patent 9,730,986, 2017 - Google Patents
The invention provides a method for alleviating discogenic pain by administering a
therapeutic agent that disrupts neuronal and/or vascular elements in the disc, which is …

Methods for modulation of autophagy through the modulation of autophagy-inhibiting gene products

J Yuan, MM Lipinski - 2011 - Google Patents
WO2011041582A2 - Methods for modulation of autophagy through the modulation of
autophagy-inhibiting gene products - Google Patents WO2011041582A2 - Methods for …

Methods for treating back or neck pain caused by NGF using a therapeutic agent consisting of ReN-1820, ALE-0540 and capsaicin

J Roy, SJ Drapeau, JC Marx - US Patent 9,789,161, 2017 - Google Patents
The invention provides a method for alleviating discogenic pain by administering a
therapeutic agent that disrupts neuronal and/or vascular elements in the disc, which is …

Medicinal agent and beverage/food for preventing cerebral dysfunction and improving same

H Hasegawa, S Aizawa - US Patent 11,173,158, 2021 - Google Patents
Disclosed is a means for improving the symptoms of a cerebral dysfunction. The present
inventors made a new discovery that the activity of brain aromatic monoamines increases …

Pharmaceutical removal of vascular extensions from a degenerating disc

J Roy, S Drapeau, J Marx - US Patent App. 11/413,346, 2007 - Google Patents
The invention provides a method for alleviating discogenic pain by administering a
therapeutic agent that disrupts neuronal and/or vascular elements in the disc, which is …

Baclofen formulation in a polyorthoester carrier

CM Hobot, ME Benz, KR Hildebrand… - US Patent 8,475,823, 2013 - Google Patents
Effective treatments of pain for extended periods of time are provided. The treatments
include the administration of one or more drug depots intraspinally wherein the drug depots …