[HTML][HTML] Crocetin: a systematic review

ZL Guo, MX Li, XL Li, P Wang, WG Wang… - Frontiers in …, 2022 - frontiersin.org
Crocetin is an aglycone of crocin naturally occurring in saffron and produced in biological
systems by hydrolysis of crocin as a bioactive metabolite. It is known to exist in several …

[HTML][HTML] Recent Advances on the Anticancer Properties of Saffron (Crocus sativus L.) and Its Major Constituents

A Lambrianidou, F Koutsougianni, I Papapostolou… - Molecules, 2020 - mdpi.com
Cancer is the second leading cause of death globally with an estimated 9.6 million deaths in
2018 and a sustained rise in its incidence in both developing and developed countries …

Crocins: A comprehensive review of structural characteristics, pharmacokinetics and therapeutic effects

Y Song, Y Wang, Y Zheng, T Liu, C Zhang - Fitoterapia, 2021 - Elsevier
Crocins, as a kind of water-soluble carotenoid pigment, are a series of ester compounds
formed from crocetin and gentibiose or glucose, and mainly distributed among Crocus …

Bioactivity and applications of saffron floral bio-residues (tepals): a natural by-product for the food, pharmaceutical, and cosmetic industries

N Belyagoubi-Benhammou, L Belyagoubi… - Critical Reviews in …, 2023 - Taylor & Francis
Saffron “Crocus sativus” is a plant of the Iridaceae family. Its therapeutic virtues have been
known since antiquity; it is used in traditional medicine and culinary preparations. It is also …

[HTML][HTML] Deciphering genetic diversity analysis of saffron (Crocus sativus L.) using RAPD and ISSR markers

MA Mir, S Mansoor, M Sugapriya, MN Alyemeni… - Saudi Journal of …, 2021 - Elsevier
The existence of genetic diversity in Crocus sativus has globally remained a mystery till date.
The study investigated PCR based DNA amplification profile of saffron using ISSR and …

[HTML][HTML] Why cancer incidence in the Arab counties is much lower than other parts of the world?

MA Arafa, KH Farhat - Journal of the Egyptian National Cancer Institute, 2022 - Springer
Despite the relatively increased cancer incidence in the last few years in the Arab countries,
it is still far from the figures reported from Western countries. Several mechanisms have …

[HTML][HTML] Insights on the role of polyphenols in combating cancer drug resistance

M Farhan - Biomedicines, 2023 - mdpi.com
Chemotherapy resistance is still a serious problem in the treatment of most cancers. Many
cellular and molecular mechanisms contribute to both inherent and acquired drug …

[HTML][HTML] Development and evaluation of crocetin-functionalized pegylated magnetite nanoparticles for hepatocellular carcinoma

S Ibrahim, B Baig, S Hisaindee, H Darwish… - Molecules, 2023 - mdpi.com
Liver cancer remains among the leading causes of cancer-related deaths worldwide. This is
due to many reasons, including limitations of available drugs, late diagnosis due to the …

Therapeutic implications of crocin in Parkinson's disease: A review of preclinical research

A Goyal, A Verma, A Agrawal, N Dubey… - Chemical Biology & …, 2023 - Wiley Online Library
Parkinson's disease is among the most common forms of neurodegenerative illness, with
present treatment being primarily symptomatic and frequently coming with substantial …

[HTML][HTML] Bioanalytical method development and validation study of neuroprotective extract of kashmiri saffron using ultra-fast liquid chromatography-tandem mass …

A Girme, S Pawar, C Ghule, S Shengule, G Saste… - Molecules, 2021 - mdpi.com
Kashmir saffron (Crocus sativus L.), also known as Indian saffron, is an important Asian
medicinal plant with protective therapeutic applications in brain health. The main bioactive in …