Glucocorticoids regulate fundamental processes of the human body and control cellular
functions such as cell metabolism, growth, differentiation, and apoptosis. Moreover …

Although oral tolerance is the normal physiologic response to ingested antigens, a
breakdown in this process appears to have occurred in the past 2 decades, leading to an …

Human lungs enable efficient gas exchange and form an interface with the environment,
which depends on mucosal immunity for protection against infectious agents. Tightly …

CD4+ T helper (TH) cells and regulatory T (Treg) cells that respond to common allergens
play an important role in driving and dampening airway inflammation in patients with …

Asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) or without (CRSsNP) are
chronic respiratory diseases. These two disorders often co-exist based on common …

Abstract Background Treg/Th17 imbalance plays an essential role in the pathogenesis of
asthma. Disordered LncRNAs were observed in asthma, however, whether LncRNAs can …

Background Little is currently known regarding the immunologic mechanism (s) that initiate
peanut allergy. Notably, peanut proteins have been detected in house dust, and their levels …

To elucidate the mechanisms underlying the reduced incidence of brain tumors in children
with Neurofibromatosis type 1 (NF1) and asthma, we leverage Nf1 optic pathway glioma …

Plant-derived extracellular vesicles,(EVs), have recently gained attention as potential
therapeutic candidates. However, the varying properties of plants that are dependent on …

For many decades, T helper 2 (TH2) cells have been considered to predominantly regulate
the pathogenic manifestations of allergic asthma, such as IgE-mediated sensitization, airway …