Rheumatoid arthritis: extra-articular manifestations and comorbidities

FA Figus, M Piga, I Azzolin, R McConnell… - Autoimmunity reviews, 2021 - Elsevier
Although synovitis is the pathological hallmark of rheumatoid arthritis (RA), many extra-
articular manifestations (EMs) and comorbidities likely occur due to the complex, chronic …

[HTML][HTML] Combating physical inactivity during the COVID-19 pandemic

AJ Pinto, DW Dunstan, N Owen, E Bonfá… - Nature Reviews …, 2020 - nature.com
Physical inactivity is common during periods of self-isolation, but for patients with rheumatic
diseases, there are crucial benefits to be gained from maintaining an active lifestyle …

Hypertension: do inflammation and immunity hold the key to solving this epidemic?

MS Madhur, F Elijovich, MR Alexander, A Pitzer… - Circulation …, 2021 - Am Heart Assoc
Elevated cardiovascular risk including stroke, heart failure, and heart attack is present even
after normalization of blood pressure in patients with hypertension. Underlying immune cell …

[HTML][HTML] Cardiovascular risk in inflammatory arthritis: rheumatoid arthritis and gout

R Hansildaar, D Vedder, M Baniaamam… - The Lancet …, 2021 - thelancet.com
The increased risk of cardiovascular morbidity and mortality in rheumatoid arthritis and gout
has been increasingly acknowledged in past decades, with accumulating evidence that …

Atherosclerotic cardiovascular disease prevention in rheumatoid arthritis

AG Semb, E Ikdahl, G Wibetoe, C Crowson… - Nature Reviews …, 2020 - nature.com
Patients with rheumatoid arthritis (RA) are at high risk of developing cardiovascular disease
(CVD). Inflammation has a pivotal role in the pathogenesis of CVD. RA is an inflammatory …

Cardiovascular comorbidity in rheumatic diseases

MT Nurmohamed, M Heslinga, GD Kitas - Nature Reviews …, 2015 - nature.com
Patients with rheumatoid arthritis (RA) and other inflammatory joint diseases (IJDs) have an
increased risk of premature death compared with the general population, mainly because of …

ACCF/AHA 2011 expert consensus document on hypertension in the elderly: a report of the American College of Cardiology Foundation Task Force on Clinical Expert …

WS Aronow, JL Fleg, CJ Pepine, NT Artinian, G Bakris… - Circulation, 2011 - Am Heart Assoc
This document was written with the intent to be a complete reference at the time of
publication on the topic of managing hypertension in the elderly. Given the length of the …

EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis

MJL Peters, DPM Symmons, D McCarey… - Annals of the …, 2010 - ard.bmj.com
Objectives: To develop evidence-based EULAR recommendations for cardiovascular (CV)
risk management in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and …

Interleukin 17 promotes angiotensin II–induced hypertension and vascular dysfunction

MS Madhur, HE Lob, LA McCann, Y Iwakura… - …, 2010 - Am Heart Assoc
We have shown previously that T cells are required for the full development of angiotensin II–
induced hypertension. However, the specific subsets of T cells that are important in this …

Rheumatoid arthritis and cardiovascular disease

CS Crowson, KP Liao, JM Davis III, DH Solomon… - American heart …, 2013 - Elsevier
Background Rheumatic disease and heart disease share common underpinnings involving
inflammation. The high levels of inflammation that characterize rheumatic diseases provide …