[HTML][HTML] Recent advances in sensing the inter-biomolecular interactions at the nanoscale–A comprehensive review of AFM-based force spectroscopy
Biomolecular interactions underpin most processes inside the cell. Hence, a precise and
quantitative understanding of molecular association and dissociation events is crucial, not …
quantitative understanding of molecular association and dissociation events is crucial, not …
Glycosylated gold nanoparticles in point of care diagnostics: From aggregation to lateral flow
AN Baker, GW Hawker-Bond, PG Georgiou… - Chemical Society …, 2022 - pubs.rsc.org
Current point-of-care lateral flow immunoassays, such as the home pregnancy test, rely on
proteins as detection units (eg antibodies) to sense for analytes. Glycans play a fundamental …
proteins as detection units (eg antibodies) to sense for analytes. Glycans play a fundamental …
The SARS-COV-2 spike protein binds sialic acids and enables rapid detection in a lateral flow point of care diagnostic device
There is an urgent need to understand the behavior of the novel coronavirus (SARS-COV-2),
which is the causative agent of COVID-19, and to develop point-of-care diagnostics. Here, a …
which is the causative agent of COVID-19, and to develop point-of-care diagnostics. Here, a …
Automation and data-driven design of polymer therapeutics
Polymers are uniquely suited for drug delivery and biomaterial applications due to tunable
structural parameters such as length, composition, architecture, and valency. To facilitate …
structural parameters such as length, composition, architecture, and valency. To facilitate …
Plasmonic detection of SARS-CoV-2 spike protein with polymer-stabilized glycosylated gold nanorods
The COVID-19 pandemic has highlighted the need for innovative biosensing, diagnostic,
and surveillance platforms. Here we report that glycosylated, polymer-stabilized, gold …
and surveillance platforms. Here we report that glycosylated, polymer-stabilized, gold …
State-of-the-Art of Nanodiagnostics and Nanotherapeutics against SARS-CoV-2
MA Derakhshan, A Amani… - ACS applied materials & …, 2021 - ACS Publications
The pandemic outbreak of SARS-CoV-2, with millions of infected patients worldwide, has
severely challenged all aspects of public health. In this regard, early and rapid detection of …
severely challenged all aspects of public health. In this regard, early and rapid detection of …
Plasmonic properties of colloidal assemblies
The assembly of metal nanoparticles into supracolloidal structures unlocks optical features,
which can go beyond synergistic combinations of the properties of their primary building …
which can go beyond synergistic combinations of the properties of their primary building …
Engineering micro–nanomaterials for biomedical translation
Engineered nano–bio interfaces–driven by vertical micro/nanoneedles, nanoparticles, organ‐
on‐chip devices, and a diversity of nanosubstrates for mass spectroscopy imaging–are …
on‐chip devices, and a diversity of nanosubstrates for mass spectroscopy imaging–are …
Toward glycomaterials with selectivity as well as affinity
SJ Richards, MI Gibson - JACS Au, 2021 - ACS Publications
Multivalent glycosylated materials (polymers, surfaces, and particles) often show high affinity
toward carbohydrate binding proteins (eg, lectins) due to the nonlinear enhancement from …
toward carbohydrate binding proteins (eg, lectins) due to the nonlinear enhancement from …
Introducing affinity and selectivity into galectin-targeting nanoparticles with fluorinated glycan ligands
SJ Richards, T Keenan, JB Vendeville… - Chemical …, 2021 - pubs.rsc.org
Galectins are potential biomarkers and therapeutic targets. However, galectins display
broad affinity towards β-galactosides meaning glycan-based (nano) biosensors lack the …
broad affinity towards β-galactosides meaning glycan-based (nano) biosensors lack the …