A review of Dengvaxia®: development to deployment

SJ Thomas, IK Yoon - Human vaccines & immunotherapeutics, 2019 - Taylor & Francis
Dengue is the world's most prevalent and important arboviral disease. More than 50% of the
world's population lives at daily risk of infection and it is estimated more than 95 million …

Beyond chemoreception: diverse tasks of soluble olfactory proteins in insects

P Pelosi, I Iovinella, J Zhu, G Wang… - Biological Reviews, 2018 - Wiley Online Library
Odorant‐binding proteins (OBPs) and chemosensory proteins (CSPs) are regarded as
carriers of pheromones and odorants in insect chemoreception. These proteins are typically …

Aedes aegypti NeSt1 Protein Enhances Zika Virus Pathogenesis by Activating Neutrophils

AK Hastings, R Uraki, H Gaitsch, K Dhaliwal… - Journal of …, 2019 - Am Soc Microbiol
Saliva from the mosquito vector of flaviviruses is capable of changing the local immune
environment, leading to an increase in flavivirus-susceptible cells at the infected bite site. In …

Aedes–Chikungunya Virus Interaction: Key Role of Vector Midguts Microbiota and Its Saliva in the Host Infection

VVS Monteiro, KC Navegantes-Lima… - Frontiers in …, 2019 - frontiersin.org
Aedes mosquitoes are important vectors for emerging diseases caused by arboviruses, such
as chikungunya (CHIKV). These viruses' main transmitting species are Aedes aegypti and …

A salivary protein of Aedes aegypti promotes dengue-2 virus replication and transmission

C Sri-In, SC Weng, WY Chen, BA Wu-Hsieh… - Insect biochemistry and …, 2019 - Elsevier
Although dengue is the most prevalent arthropod-borne viral disease in humans, no
effective medication or vaccine is presently available. Previous studies suggested that …

Identification of Aedes aegypti salivary gland proteins interacting with human immune receptor proteins

E Gavor, YK Choong, Y Liu, J Pompon… - PLoS Neglected …, 2022 - journals.plos.org
Mosquito saliva proteins modulate the human immune and hemostatic systems and control
mosquito-borne pathogenic infections. One mechanism through which mosquito proteins …

Immuno-informatics guided designing of a multi-epitope vaccine against Dengue and Zika

A Bhardwaj, R Sharma, A Grover - Journal of Biomolecular …, 2023 - Taylor & Francis
Dengue and zika are amongst the most prevalent mosquito-borne diseases caused by
closely related members Dengue virus (DENV) and Zika virus (ZIKV), respectively, of the …

Multiple Salivary Proteins from Aedes aegypti Mosquito Bind to the Zika Virus Envelope Protein

PC Valenzuela-Leon, G Shrivastava, I Martin-Martin… - Viruses, 2022 - mdpi.com
Aedes aegypti mosquitoes are important vectors of several debilitating and deadly arthropod-
borne (arbo) viruses, including Yellow Fever virus, Dengue virus, West Nile virus and Zika …

Allergenome characterization of the mosquito Aedes aegypti

JF Cantillo, L Puerta, P Puchalska, S Lafosse‐Marin… - Allergy, 2017 - Wiley Online Library
Background Saliva and muscle‐derived mosquito allergens have been purified and
characterized. However, the complete set of allergens remains to be elucidated. In this …

Mosquito-Borne Diseases and Omics: Salivary Gland Proteome of the Female Aedes aegypti Mosquito

R Dhawan, M Kumar, AK Mohanty, G Dey… - OMICS: A Journal of …, 2017 - liebertpub.com
The female Aedes aegypti mosquito is an important vector for several tropical and
subtropical diseases such as dengue, chikungunya, and Zika and yellow fever. The disease …