In vivo electrochemical sensing based on implantable microelectrodes is a strong driving
force of analytical neurochemistry in brain. The complex and dynamic neurochemical …

Abstracts Functional connectivity, which reflects the spatial and temporal organization of
intrinsic activity throughout the brain, is one of the most studied measures in human …

Monitoring regional tissue oxygenation in animal models and potentially in human subjects
can yield insights into the underlying mechanisms of local O2-mediated physiological …

Rationale Xylazine has emerged in recent years as an adulterant in an increasing number of
opioid-positive overdose deaths in the United States. Although its exact role in opioid …

Hydrogen peroxide is a major redox signaling molecule underlying a novel paradigm of cell
function and communication. A role for H 2 O 2 as an intercellular signaling molecule and …

Implantable electrochemical sensors provide reliable tools for in vivo brain research. Recent
advances in electrode surface design and high-precision fabrication of devices led to …

The ability to monitor the chemical composition of brain interstitial fluid remains an important
challenge in the field of bioanalytical chemistry. In particular, microelectrode biosensors are …

The small and diffusible free radical nitric oxide (• NO) has fascinated biological and medical
sciences since it was promoted from atmospheric air pollutant to biological ubiquitous …

Epilepsy is a prevalent neurological disorder with a complex pathogenesis and
unpredictable nature, presenting limited treatment options in> 30% of affected individuals …

Background Although GABA is the major inhibitory neurotransmitter in the CNS, quantifying
in vivo GABA levels has been challenging. The ability to co-monitor both GABA and the …