The glutathione S-transferases (GST) represent a major group of detoxification enzymes. All
eukaryotic species possess multiple cytosolic and membrane-bound GST isoenzymes, each …

The mechanisms by which brassica vegetables might decrease the risk of cancer are
reviewed in this paper. Brassicas, including all types of cabbages, broccoli, cauliflower and …

Indole-3-carbinol (I3C) is produced by members of the family Cruciferae, and particularly
members of the genus Brassica (eg, cabbage, radishes, cauliflower, broccoli, Brussels …

Glucosinolates in crop plants Page 116 Glucosinolates in Crop Plants EAS Rosa Horticulture
Section Universidade de Trás-os-Montes e Alto Douro Vila Real, Portugal RK Heaney and …

Phytochemicals such as indole-3-carbinol (I3C) and sulforaphane are components of
cruciferous vegetables which exhibit antitumorigenic activity associated with altered …

Abstract Indole-3-carbinol (I3C) and 3, 3′-diindolylmethane (DIM) are promising cancer
chemopreventive agents in rodent models, but there is a paucity of data on their …

Clinical chemoprevention trials of more than 30 agents and agent combinations are now in
progress or being planned. The most advanced agents are well known and are in large …

Consumption of plants of the species Brassica oleracea is related to a decreased incidence
of certain cancer forms in humans, and this has been linked to the presence of …

Presystemic metabolism occurring in the intestinal epithelium and/or liver is frequently an
important determinant of drug bioavailability after oral administration. Several factors are …

Cruciferous vegetables contain secondary metabolites termed glucosinolates that break
down to products that upregulate hepatic detoxification enzymes. We have previously shown …