Phytochemical, Therapeutic, and Ethnopharmacological Overview for a Traditionally Important Herb: Boerhavia diffusa Linn.

S Mishra, V Aeri, PK Gaur… - BioMed research …, 2014 - Wiley Online Library
Boerhavia diffusa (BD) is a plant of rasayana category as per ayurvedic claims. It is reported
to possess antiaging, disease prevention, and life strengthening activities which hold …

Medicinal plants and natural products in amelioration of arsenic toxicity: a short review

S Bhattacharya - Pharmaceutical biology, 2017 - Taylor & Francis
Context: Chronic arsenic toxicity (arsenicosis) is considered a serious public health menace
worldwide, as there is no specific, safe, and efficacious therapeutic management of …

Arsenic cardiotoxicity: an overview

NS Alamolhodaei, K Shirani, G Karimi - Environmental toxicology and …, 2015 - Elsevier
Arsenic, a naturally ubiquitous element, is found in foods and environment. Cardiac
dysfunction is one of the major causes of morbidity and mortality in the world. Arsenic …

[HTML][HTML] Assessing drug-induced mitochondrial toxicity in cardiomyocytes: implications for preclinical cardiac safety evaluation

X Tang, Z Wang, S Hu, B Zhou - Pharmaceutics, 2022 - mdpi.com
Drug-induced cardiotoxicity not only leads to the attrition of drugs during development, but
also contributes to the high morbidity and mortality rates of cardiovascular diseases …

[HTML][HTML] Ethnomedicinal values of Boerhaavia diffusa L. as a panacea against multiple human ailments: a state of art review

S Das, PK Singh, S Ameeruddin… - Frontiers in …, 2023 - frontiersin.org
Ethnopharmacological relevance: Therapeutic botanicals (plants and derivatives) are in use
since antiquity for various health ailments. The ethnic community is the repository of the …

[HTML][HTML] Antioxidants protect against arsenic induced mitochondrial cardio-toxicity

C Pace, R Dagda, J Angermann - Toxics, 2017 - mdpi.com
Arsenic is a potent cardiovascular toxicant associated with numerous biomarkers of
cardiovascular diseases in exposed human populations. Arsenic is also a carcinogen, yet …

[HTML][HTML] Protective Effect of Boerhaavia diffusa L. against Mitochondrial Dysfunction in Angiotensin II Induced Hypertrophy in H9c2 Cardiomyoblast Cells

A Prathapan, VP Vineetha, KG Raghu - PLoS One, 2014 - journals.plos.org
Mitochondrial dysfunction plays a critical role in the development of cardiac hypertrophy and
heart failure. So mitochondria are emerging as one of the important druggable targets in the …

An overview on arsenic trioxide-induced cardiotoxicity

VP Vineetha, KG Raghu - Cardiovascular Toxicology, 2019 - Springer
Arsenic trioxide (ATO) is among the first-line chemotherapeutic drugs used in oncological
practice. It has shown substantial efficacy in treating patients with relapsed or refractory …

[HTML][HTML] Potential of natural products in combination with arsenic trioxide: Investigating cardioprotective effects and mechanisms

J Wang, YM Liu, J Hu, C Chen - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Over the past few decades, clinical trials conducted worldwide have demonstrated the
efficacy of arsenic trioxide (ATO) in the treatment of relapsed acute promyelocytic leukemia …

Influence of mitochondrion-toxic agents on the cardiovascular system

J Finsterer, P Ohnsorge - Regulatory Toxicology and Pharmacology, 2013 - Elsevier
Cardiovascular disease may be induced or worsened by mitochondrion-toxic agents.
Mitochondrion-toxic agents may be classified as those with or without a clinical effect, those …