[HTML][HTML] MicroRNAs in cardiovascular disease: an introduction for clinicians
SPR Romaine, M Tomaszewski, G Condorelli… - Heart, 2015 - heart.bmj.com
MicroRNAs (miRNAs) are small, non-coding, RNA molecules approximately 22 nucleotides
in length which act as post-transcriptional regulators of gene expression. Individual miRNAs …
in length which act as post-transcriptional regulators of gene expression. Individual miRNAs …
MicroRNAs: roles in cardiovascular development and disease
Cardiovascular diseases (CVDs) comprise a group of disorders ranging from peripheral
artery, coronary artery, cardiac valve, cardiac muscle, and congenital heart diseases to …
artery, coronary artery, cardiac valve, cardiac muscle, and congenital heart diseases to …
Distribution of miRNA expression across human tissues
We present a human miRNA tissue atlas by determining the abundance of 1997 miRNAs in
61 tissue biopsies of different organs from two individuals collected post-mortem. One …
61 tissue biopsies of different organs from two individuals collected post-mortem. One …
MicroRNA as an important target for anticancer drug development
Z Fu, L Wang, S Li, F Chen, KKW Au-Yeung… - Frontiers in …, 2021 - frontiersin.org
Cancer has become the second greatest cause of death worldwide. Although there are
several different classes of anticancer drugs that are available in clinic, some tough issues …
several different classes of anticancer drugs that are available in clinic, some tough issues …
[HTML][HTML] MicroRNA and cardiovascular diseases
HA Çakmak, M Demir - Balkan medical journal, 2020 - ncbi.nlm.nih.gov
Cardiovascular diseases are one of the most common causes of death in both developing
and developed countries worldwide. Even though there have been improvements in primary …
and developed countries worldwide. Even though there have been improvements in primary …
Circulating microRNAs: Biomarkers of disease
Y Wu, Q Li, R Zhang, X Dai, W Chen, D Xing - Clinica Chimica Acta, 2021 - Elsevier
MicroRNAs are a class of endogenous noncoding single-stranded RNA molecules with
approximately 20–24 nucleotides and are associated with a broad range of biological …
approximately 20–24 nucleotides and are associated with a broad range of biological …
MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy
J Halkein, SP Tabruyn, M Ricke-Hoch… - The Journal of …, 2013 - Am Soc Clin Investig
Peripartum cardiomyopathy (PPCM) is a life-threatening pregnancy-associated
cardiomyopathy in previously healthy women. Although PPCM is driven in part by the 16 …
cardiomyopathy in previously healthy women. Although PPCM is driven in part by the 16 …
Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies
Cardiac hypertrophy can be defined as an increase in heart mass. Pathological cardiac
hypertrophy (heart growth that occurs in settings of disease, eg hypertension) is a key risk …
hypertrophy (heart growth that occurs in settings of disease, eg hypertension) is a key risk …
[HTML][HTML] The role of microRNAs in human diseases
AM Ardekani, MM Naeini - Avicenna journal of medical …, 2010 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are short RNA molecules which bind to target mRNAs, resulting in
translational repression and gene silencing and are found in all eukaryotic cells …
translational repression and gene silencing and are found in all eukaryotic cells …
Role of flow-sensitive microRNAs in endothelial dysfunction and atherosclerosis: mechanosensitive athero-miRs
S Kumar, CW Kim, RD Simmons… - … , thrombosis, and vascular …, 2014 - Am Heart Assoc
Atherosclerosis preferentially occurs in arterial regions exposed to disturbed flow, in part,
due to alterations in gene expression. MicroRNAs (miRNAs) are small, noncoding genes …
due to alterations in gene expression. MicroRNAs (miRNAs) are small, noncoding genes …