Visible-to-NIR-light activated release: from small molecules to nanomaterials
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
Photodynamic nanomedicine in the treatment of solid tumors: perspectives and challenges
Photodynamic therapy (PDT) is a promising treatment strategy where activation of
photosensitizer drugs with specific wavelengths of light results in energy transfer cascades …
photosensitizer drugs with specific wavelengths of light results in energy transfer cascades …
Delivery of the photosensitizer Pc 4 in PEG–PCL micelles for in vitro PDT studies
AM Master, ME Rodriguez, ME Kenney… - Journal of …, 2010 - Elsevier
The silicon phthalocyanine Pc 4 is a second-generation photosensitizer that has several
properties superior to other photosensitizers currently approved by the FDA, and it has …
properties superior to other photosensitizers currently approved by the FDA, and it has …
Structural Factors and Mechanisms Underlying the Improved Photodynamic Cell Killing with Silicon Phthalocyanine Photosensitizers Directed to Lysosomes Versus …
ME Rodriguez, P Zhang, K Azizuddin… - Photochemistry and …, 2009 - Wiley Online Library
The phthalocyanine photosensitizer Pc 4 has been shown to bind preferentially to
mitochondrial and endoplasmic reticulum membranes. Upon photoirradiation of Pc 4 …
mitochondrial and endoplasmic reticulum membranes. Upon photoirradiation of Pc 4 …
EGFR-mediated intracellular delivery of Pc 4 nanoformulation for targeted photodynamic therapy of cancer: in vitro studies
In photodynamic therapy (PDT), the light activation of a photosensitizer leads to the
generation of reactive oxygen species that can trigger various mechanisms of cell death …
generation of reactive oxygen species that can trigger various mechanisms of cell death …
Amphiphilic phthalocyanines in polymeric micelles: A supramolecular approach toward efficient third-generation photosensitizers
F Setaro, JWH Wennink, PI Mäkinen… - Journal of Materials …, 2020 - pubs.rsc.org
In this paper we describe a straightforward supramolecular strategy to encapsulate silicon
phthalocyanine (SiPc) photosensitizers (PS) in polymeric micelles made of poly (ε …
phthalocyanine (SiPc) photosensitizers (PS) in polymeric micelles made of poly (ε …
Potential of porous silicon nanoparticles as an emerging platform for cancer theranostics
V Stojanovic, F Cunin, JO Durand, M Garcia… - Journal of Materials …, 2016 - pubs.rsc.org
Currently, nanoscience is a major part of biomedical research, due to material advances that
aid the development of new tools and techniques to replace traditional methods. To this end …
aid the development of new tools and techniques to replace traditional methods. To this end …
Optimization of a nanomedicine-based silicon phthalocyanine 4 photodynamic therapy (Pc 4-PDT) strategy for targeted treatment of EGFR-overexpressing cancers
AM Master, M Livingston, NL Oleinick… - Molecular …, 2012 - ACS Publications
The current clinical mainstays for cancer treatment, namely, surgical resection,
chemotherapy, and radiotherapy, can cause significant trauma, systemic toxicity, and …
chemotherapy, and radiotherapy, can cause significant trauma, systemic toxicity, and …
Real-time, in vivo measurement of tissular through the delayed fluorescence of endogenous protoporphyrin IX during photodynamic therapy
F Piffaretti, AM Novello, RS Kumar… - … of biomedical optics, 2012 - spiedigitallibrary.org
Tissular oxygen concentration plays a key role during photodynamic therapy (PDT).
Therefore, monitoring its local oxygen partial pressure (pO 2) may help predict and/or control …
Therefore, monitoring its local oxygen partial pressure (pO 2) may help predict and/or control …
Observation and Photophysical Characterization of Silicon Phthalocyanine J‐Aggregate Dimers in Aqueous Solutions
T Doane, A Chomas, S Srinivasan… - Chemistry–A European …, 2014 - Wiley Online Library
The use of macrocyclic molecules for both imaging and photodynamic therapy (PDT) has
proven to be a powerful method for assessing and treating diseases, respectively. However …
proven to be a powerful method for assessing and treating diseases, respectively. However …