Cardiovascular disease (CVD) and cancer are the leading causes of death worldwide. With
an increasing number of the elderly population, and early cancer screening and treatment …

Quinacrine, also known as mepacrine, has originally been used as an antimalarial drug for
close to a century, but was recently rediscovered as an anticancer agent. The mechanisms …

Background Despite the accumulation of research papers on aspirin and cancer, there is
doubt as to whether or not aspirin is an acceptable and effective adjunct treatment of cancer …

Background To assess the completeness of reporting, research transparency practices, and
risk of selection and immortal bias in observational studies using routinely collected data for …

We evaluated the association between aspirin, statins, and metformin use and prostate
cancer (PC) incidence and mortality using a large population-based dataset. 388,760 men …

Background and aim: For a long time, aspirin has been recommended for the prevention of
cardiovascular disease (CVD). However, results of long-term effects of aspirin use on the …

Background and objective: Long-term aspirin use for the primary prevention of cancer
remains controversial, and variations in the effect of aspirin use on cancer outcomes by …

Chronic inflammation is a major cause of human cancers. The environmental factors, such
as microbiome, dietary components, and obesity, provoke chronic inflammation in the …

Abstract Background In Denmark, the Cancer Patient Pathway for Non-Specific Signs and
Symptoms (NSSC-CPP) has been implemented with variations: in some areas, general …

The Hippo signaling pathway has a regulatory function in the organogenesis process and
cellular homeostasis, switching the cascade reactions of crucial kinases acts to turn off/on …