The importance of neuronal morphology in brain function has been recognized for over a
century. The broad applicability of" digital reconstructions" of neuron morphology across …

The importance of neuronal morphology has been recognized from the early days of
neuroscience. Elucidating the functional roles of axonal and dendritic arbors in synaptic …

To facilitate fine-scale phenotyping of whole specimens, we describe here a set of tissue
fixation-embedding, detergent-clearing and staining protocols that can be used to transform …

Abstract Open-Source 3D Visualization-Assisted Analysis (Vaa3D) is a software platform for
the visualization and analysis of large-scale multidimensional images. In this protocol we …

Brain circuit mapping requires digital reconstruction of neuronal morphologies in
complicated networks. Despite recent advances in automatic algorithms, reconstruction of …

The classification of neurons into types has been much debated since the inception of
modern neuroscience. Recent experimental advances are accelerating the pace of data …

Advances in optical microscopy, biosensors and cell culturing technologies have
transformed live cell imaging. Thanks to these advances live cell imaging plays an …

Recent technological advancements have facilitated the imaging of specific neuronal
populations at the single-axon level across the mouse brain. However, the digital …

Digital reconstructions of neuronal morphology are used to study neuron function,
development, and responses to various conditions. Although many measures exist to …

Motivation From image stacks to computational models, processing digital representations of
neuronal morphologies is essential to neuroscientific research. Workflows involve various …