Incidence of narcolepsy after H1N1 influenza and vaccinations: systematic review and meta-analysis

TO Sarkanen, APE Alakuijala, YA Dauvilliers… - Sleep medicine …, 2018 - Elsevier
An increased incidence of narcolepsy was seen in many countries after the pandemic H1N1
influenza vaccination campaign in 2009–2010. The H1N1 vaccine–narcolepsy connection is …

NREM sleep parasomnias as disorders of sleep-state dissociation

A Castelnovo, R Lopez, P Proserpio, L Nobili… - Nature Reviews …, 2018 - nature.com
Non-rapid eye movement (NREM) sleep parasomnias (or NREM parasomnias) are
fascinating disorders with mysterious neurobiological substrates. These conditions are …

T cells in patients with narcolepsy target self-antigens of hypocretin neurons

D Latorre, U Kallweit, E Armentani, M Foglierini, F Mele… - Nature, 2018 - nature.com
Narcolepsy is a chronic sleep disorder caused by the loss of neurons that produce
hypocretin. The close association with HLA-DQB1* 06: 02, evidence for immune …

[图书][B] Psicopatologia e semiologia dos transtornos mentais

P Dalgalarrondo - 2018 - books.google.com
Page 1 Atualizado de acordo com O DSM-5 e a CID-11 Paulo Dalgalarrondo PSICO patologia
e Semiologia dOs TranstOrnOs Mentais Page 2 Aviso Todo esforço foi feito para garantir a …

AS03 adjuvanted AH1N1 vaccine associated with an abrupt increase in the incidence of childhood narcolepsy in Finland

H Nohynek, J Jokinen, M Partinen, O Vaarala… - PloS one, 2012 - journals.plos.org
Background Narcolepsy is a chronic sleep disorder with strong genetic predisposition
causing excessive daytime sleepiness and cataplexy. A sudden increase in childhood …

Pitolisant versus placebo or modafinil in patients with narcolepsy: a double-blind, randomised trial

Y Dauvilliers, C Bassetti, GJ Lammers, I Arnulf… - The Lancet …, 2013 - thelancet.com
Background Narcolepsy is characterised by excessive daytime sleepiness (EDS) and
cataplexy. Histamine neurons are crucial to maintain wakefulness. We assessed the safety …

GHB pharmacology and toxicology: acute intoxication, concentrations in blood and urine in forensic cases and treatment of the withdrawal syndrome

F P. Busardo, A W. Jones - Current neuropharmacology, 2015 - benthamdirect.com
The illicit recreational drug of abuse, γ-hydroxybutyrate (GHB) is a potent central nervous
system depressant and is often encountered during forensic investigations of living and …

Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination

M Partinen, BR Kornum, G Plazzi, P Jennum… - The Lancet …, 2014 - thelancet.com
Narcolepsy is a sleep disorder characterised by loss of hypothalamic hypocretin (orexin)
neurons. The prevalence of narcolepsy is about 30 per 100 000 people, and typical age at …

Increased incidence and clinical picture of childhood narcolepsy following the 2009 H1N1 pandemic vaccination campaign in Finland

M Partinen, O Saarenpää-Heikkilä, I Ilveskoski… - PloS one, 2012 - journals.plos.org
Background Narcolepsy is a rare neurological sleep disorder especially in children who are
younger than 10 years. In the beginning of 2010, an exceptionally large number of Finnish …

Unraveling the evolutionary determinants of sleep

WJ Joiner - Current biology, 2016 - cell.com
Despite decades of intense study, the functions of sleep are still shrouded in mystery. The
difficulty in understanding these functions can be at least partly attributed to the varied …