A common feature of pesticides: oxidative stress—the role of oxidative stress in pesticide‐induced toxicity

RO Sule, L Condon, AV Gomes - Oxidative medicine and …, 2022 - Wiley Online Library
Pesticides are important chemicals or biological agents that deter or kill pests. The use of
pesticides has continued to increase as it is still considered the most effective method to …

[HTML][HTML] Neurotoxicity of pesticides–A link to neurodegeneration

B Vellingiri, M Chandrasekhar, SS Sabari… - Ecotoxicology and …, 2022 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder which mainly targets motor
symptoms such as tremor, rigidity, bradykinesia and postural instability. The physiological …

Spontaneous reduction-induced degradation of viologen compounds in water microdroplets and its inhibition by host–guest complexation

C Gong, D Li, X Li, D Zhang, D Xing… - Journal of the …, 2022 - ACS Publications
Water serves as an inert environment for the dispersion and application of many kinds of
herbicides. Viologen compounds, a type of widely used but highly toxic herbicide, are stable …

[HTML][HTML] Parkinson's disease: animal models and dopaminergic cell vulnerability

J Blesa, S Przedborski - Frontiers in neuroanatomy, 2014 - frontiersin.org
Parkinson's disease (PD) is a neurodegenerative disorder that affects about 1.5% of the
global population over 65 years of age. A hallmark feature of PD is the degeneration of the …

[HTML][HTML] Parkinson's disease: mechanisms and models

W Dauer, S Przedborski - Neuron, 2003 - cell.com
Parkinson's disease (PD) results primarily from the death of dopaminergic neurons in the
substantia nigra. Current PD medications treat symptoms; none halt or retard dopaminergic …

Pesticides exposure as etiological factors of Parkinson's disease and other neurodegenerative diseases—a mechanistic approach

MT Baltazar, RJ Dinis-Oliveira, M de Lourdes Bastos… - Toxicology letters, 2014 - Elsevier
The etiology of most neurodegenerative disorders is multifactorial and consists of an
interaction between environmental factors and genetic predisposition. The role of pesticide …

Classic and new animal models of Parkinson′ s disease

J Blesa, S Phani, V Jackson-Lewis… - BioMed Research …, 2012 - Wiley Online Library
Neurological disorders can be modeled in animals so as to recreate specific pathogenic
events and behavioral outcomes. Parkinson's Disease (PD) is the second most common …

Neurotoxin-based models of Parkinson's disease

J Bové, C Perier - Neuroscience, 2012 - Elsevier
Animal experimentation in the Parkinson's disease (PD) field is a classic example of how the
use of animal models to study diseases can have a significant impact on human health …

Paraquat poisonings: mechanisms of lung toxicity, clinical features, and treatment

RJ Dinis-Oliveira, JA Duarte… - Critical reviews in …, 2008 - Taylor & Francis
Paraquat dichloride (methyl viologen; PQ) is an effective and widely used herbicide that has
a proven safety record when appropriately applied to eliminate weeds. However, over the …

Physiology of nitric oxide in skeletal muscle

JS Stamler, G Meissner - Physiological reviews, 2001 - journals.physiology.org
In the past five years, skeletal muscle has emerged as a paradigm of “nitric oxide”(NO)
function and redox-related signaling in biology. All major nitric oxide synthase (NOS) …