Maintenance of endothelial cell integrity is an important component of human health and
disease since the endothelium can perform various functions including regulation of …

Oxidative stress (OS), defined as disturbances in the pro-/antioxidant balance, is harmful to
cells due to the excessive generation of highly reactive oxygen (ROS) and nitrogen (RNS) …

The vascular endothelium is a dynamic, functionally complex organ, modulating multiple
biological processes, including vascular tone and permeability, inflammatory responses …

The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

Alterations of endothelial cells and the vasculature play a central role in the pathogenesis of
a broad spectrum of the most dreadful of human diseases, as endothelial cells have the key …

It has recently emerged that endothelial dysfunction is an early step in the development of
atherosclerosis and is mainly characterised by a reduction in the bioavailability of nitric …

The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth
muscle, by releasing vasodilator substances. The best characterized endothelium‐derived …

Endothelial cells synthesize and release various factors that regulate angiogenesis,
inflammatory responses, hemostasis, as well as vascular tone and permeability. Endothelial …

Endothelium plays a crucial role in the maintenance of vascular tone and structure.
Endothelial dysfunction is known to precede overt coronary artery disease. A number of …

Endothelium is the largest organ in the body strategically located between the wall of blood
vessels and the blood stream. The human body contains approximately 1013 endothelial …