[HTML][HTML] Mechanisms underlying neurodegenerative disorders and potential neuroprotective activity of agrifood by-products

C Angeloni, M Malaguti, C Prata, M Freschi… - Antioxidants, 2022 - mdpi.com
Neurodegenerative diseases, characterized by progressive loss in selected areas of the
nervous system, are becoming increasingly prevalent worldwide due to an aging population …

[HTML][HTML] Agri-food waste from apple, pear, and sugar beet as a source of protective bioactive molecules for endothelial dysfunction and its major complications

C Caliceti, M Malaguti, L Marracino, MC Barbalace… - Antioxidants, 2022 - mdpi.com
Endothelial damage is recognized as the initial step that precedes several cardiovascular
diseases (CVD), such as atherosclerosis, hypertension, and coronary artery disease. It has …

Bioactive phytocompounds for oral cancer prevention and treatment: A comprehensive and critical evaluation

JT Burcher, LK DeLiberto, AM Allen… - Medicinal Research …, 2023 - Wiley Online Library
The high incidence of oral cancer combined with excessive treatment cost underscores the
need for novel oral cancer preventive and therapeutic options. The value of natural agents …

[HTML][HTML] In Vitro Investigation of the Anticancer Properties of Ammodaucus Leucotrichus Coss. & Dur.

M Lenzi, E Turrini, E Catanzaro, V Cocchi, A Guerrini… - Pharmaceuticals, 2022 - mdpi.com
Little is known about the pharmacological activity of Ammodaucus leucotrichus Coss. & Dur.,
a small annual species that grows in the Saharan and sub-Saharan countries. In the present …

[HTML][HTML] Meripilus giganteus ethanolic extract exhibits pro-apoptotic and anti-proliferative effects in leukemic cell lines

M Lenzi, V Cocchi, A Novaković, M Karaman… - … and alternative medicine, 2018 - Springer
Background The interest towards botanicals and plant extracts has strongly risen due to their
numerous biological effects and ability to counteract chronic diseases development. Among …

[HTML][HTML] Oxidative Stress in Takotsubo syndrome—Is it essential for an acute attack? Indirect evidences support multisite impact including the calcium overload …

J Manousek, P Kala, P Lokaj, T Ondrus… - Frontiers in …, 2021 - frontiersin.org
Indirect evidences in reviews and case reports on Takotsubo syndrome (TTS) support the
fact that the existence of oxidative stress (OS) might be its common feature in the pre-acute …

[HTML][HTML] Anti-leukemic activity of brassica-derived bioactive compounds in HL-60 myeloid leukemia cells

MÁ Núñez-Sánchez, MA Martínez-Sánchez… - International Journal of …, 2022 - mdpi.com
Acute myeloid leukemia (AML) is a cancer of the myeloid blood cells mainly treated with
chemotherapy for cancer remission, but this non-selective treatment also induces numerous …

[HTML][HTML] 6-(Methylsulfonyl) hexyl isothiocyanate: a chemopreventive agent inducing autophagy in leukemia cell lines

V Cocchi, B Jávega, S Gasperini, JE O'Connor… - Biomolecules, 2022 - mdpi.com
Autophagy is a fundamental catabolic process of cellular survival. The role of autophagy in
cancer is highly complex: in the early stages of neoplastic transformation, it can act as a …

Wasabi 6‐(methylsulfinyl)hexyl isothiocyanate induces apoptosis in human colorectal cancer cells through p53‐independent mitochondrial dysfunction pathway

S Yano, S Wu, K Sakao, DX Hou - BioFactors, 2018 - Wiley Online Library
(Methylsulfinyl) hexyl isothiocyanate (6‐MSITC), a major bioactive compound in Wasabi
[Wasabia japonica (Miq.) Matsum.], has revealed the inhibitory effect on colon …

[HTML][HTML] Marine-derived compounds targeting topoisomerase II in cancer cells: A review

G Greco, V Pellicioni, I Cruz-Chamorro, G Attisani… - Marine Drugs, 2022 - mdpi.com
Cancer affects more than 19 million people and is the second leading cause of death in the
world. One of the principal strategies used in cancer therapy is the inhibition of …