Recent advances in design of antimicrobial peptides and polypeptides toward clinical translation
The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …
Antimicrobial drugs bearing guanidine moieties: A review
SH Kim, D Semenya, D Castagnolo - European Journal of Medicinal …, 2021 - Elsevier
Compounds incorporating guanidine moieties constitute a versatile class of biologically
interesting molecules with a wide array of applications. As such, guanidines have been …
interesting molecules with a wide array of applications. As such, guanidines have been …
Low-drug resistance carbon quantum dots decorated injectable self-healing hydrogel with potent antibiofilm property and cutaneous wound healing
P Li, S Liu, X Yang, S Du, W Tang, W Cao… - Chemical Engineering …, 2021 - Elsevier
Local bacterial infection remains an increasingly severe threat to human health worldwide,
and infection control is still a challenging task in clinics. Systemic administration of …
and infection control is still a challenging task in clinics. Systemic administration of …
[HTML][HTML] Synthetic and natural guanidine derivatives as antitumor and antimicrobial agents: A review
AR Gomes, CL Varela, AS Pires… - Bioorganic …, 2023 - Elsevier
Guanidines are fascinating small nitrogen-rich organic compounds, which have been
frequently associated with a wide range of biological activities. This is mainly due to their …
frequently associated with a wide range of biological activities. This is mainly due to their …
Low-toxicity carbon quantum dots derived from gentamicin sulfate to combat antibiotic resistance and eradicate mature biofilms
P Li, S Liu, W Cao, G Zhang, X Yang, X Gong… - Chemical …, 2020 - pubs.rsc.org
Carbon quantum dots derived from gentamicin sulfate are directly developed by facile
calcination at different temperatures. A promising nanomaterial, CQD180, even shows a …
calcination at different temperatures. A promising nanomaterial, CQD180, even shows a …
Small molecular mimetics of antimicrobial peptides as a promising therapy to combat bacterial resistance
P Teng, H Shao, B Huang, J Xie, S Cui… - Journal of Medicinal …, 2023 - ACS Publications
Clinically, antibiotics are widely used to treat infectious diseases; however, excessive drug
abuse and overuse exacerbate the prevalence of drug-resistant bacterial pathogens …
abuse and overuse exacerbate the prevalence of drug-resistant bacterial pathogens …
Battle against vancomycin-resistant bacteria: recent developments in chemical strategies
Vancomycin, a natural glycopeptide antibiotic, was used as the antibiotic of last resort for the
treatment of multidrug-resistant Gram-positive bacterial infections. However, almost 30 years …
treatment of multidrug-resistant Gram-positive bacterial infections. However, almost 30 years …
Development of bis-cyclic imidazolidine-4-one derivatives as potent antibacterial agents
Antibiotic resistance has emerged as one of the biggest public health concerns all over the
world. In an effort to combat bacterial infections, a series of imidazolidine-4-one derivatives …
world. In an effort to combat bacterial infections, a series of imidazolidine-4-one derivatives …
Antimicrobial peptide mimics for clinical use: does size matter?
The search for efficient antimicrobial therapies that can alleviate suffering caused by
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …
N-Arylimidazoliums as Highly Selective Biomimetic Antimicrobial Agents
Antibiotic resistance has become one of the greatest health threats in the world. In this study,
a charge-dispersed dimerization strategy is described for the antimicrobial peptide (AMP) …
a charge-dispersed dimerization strategy is described for the antimicrobial peptide (AMP) …