The incidence of venous thromboembolism (VTE) is well recognized to increase with aging.
Concurrently, the plasma concentrations of many coagulation factors (eg, fibrinogen, factor …

This review provides an update on laboratory testing and monitoring for existing and
emerging anticoagulants, starting with an overview of haemostasis and the routine …

BACKGROUND The calibrated automated thrombogram (CAT) assay in plasma is a
versatile tool to investigate patients with hypo-or hypercoagulable phenotypes. The …

Deep venous thrombosis and pulmonary embolism represent two expressions of a similar
clinical pathological process traditionally referred to as venous thromboembolism. Several …

One-third of patients with severe factor XI (FXI) deficiency caused by homozygosity for null
alleles develop inhibitor antibodies following exposure to plasma. Haemostasis during …

Introduction Patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) are
susceptible to haemostatic disturbances. Monitoring the haemostatic capacity by …

Abstract von Willebrand disease (VWD) is considered to be the most common inherited
bleeding disorder. VWD is diagnosed following a clinical and physical review, with personal …

Hypercoagulability plays a key role in the progression of cardiovascular disease (CVD).
Although omega-3 polyunsaturated fatty acid (PUFA) intake has been inversely related to …

Anticoagulation by a standard dosage of an inhibitor of thrombin generation presupposes
predictable pharmacokinetics and pharmacodynamics of the anticoagulant. We determined …

The current report provides a personal perspective summarising some interesting recent
developments in hemostasis, as well as providing a brief glimpse into some possible …