Sleep and its regulation: An emerging pathogenic and treatment frontier in Alzheimer's disease

BA Kent, HH Feldman, HB Nygaard - Progress in neurobiology, 2021 - Elsevier
A majority of patients with Alzheimer's disease (AD) experience some form of sleep
disruption, including nocturnal sleep fragmentation, increased daytime napping, decreased …

[HTML][HTML] Mutual interactions between brain states and alzheimer's disease pathology: a focus on gamma and slow oscillations

N Byron, A Semenova, S Sakata - Biology, 2021 - mdpi.com
Simple Summary Electrical activity in the brain dynamically changes throughout the day.
Abnormalities in brain activity have been associated with various brain disorders, including …

Sleep quality and health-related quality of life in older people with subjective cognitive decline, mild cognitive impairment, and Alzheimer disease

M Leng, H Yin, P Zhang, Y Jia, M Hu, G Li… - The Journal of …, 2020 - journals.lww.com
We aimed to investigate sleep quality and health-related quality of life (HRQOL) in older
adults with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and …

Association of β-amyloid burden with sleep dysfunction and cognitive impairment in elderly individuals with cognitive disorders

JC You, E Jones, DE Cross, AC Lyon, H Kang… - JAMA Network …, 2019 - jamanetwork.com
Importance Evidence shows that sleep dysfunction and β-amyloid (Aβ) deposition work
synergistically to impair brain function in individuals with normal cognition, increasing the …

Effects on sleep from group activity with a robotic seal for nursing home residents with dementia: a cluster randomized controlled trial

N Jøranson, C Olsen, G Calogiuri… - International …, 2021 - cambridge.org
Objectives: Sleep disturbances are common in people with dementia and increase with the
severity of the disease. Sleep disturbances are complex and caused by several factors and …

Determinants of physical functioning and health-related quality of life among sexual and gender minority older adults with cognitive impairment

HJ Kim, K Fredriksen-Goldsen… - Journal of aging and …, 2023 - journals.sagepub.com
Objectives: To examine risk and protective factors predicting physical functioning and
physical and psychological health-related quality of life (HRQOL) among sexual and gender …

Tailored music listening in persons with dementia: a feasibility randomized clinical trial

DV Petrovsky, J Bradt, MV McPhillips… - American Journal of …, 2023 - journals.sagepub.com
Introduction: This study examined the feasibility, acceptability, and preliminary efficacy of
tailored music listening intervention on sleep disturbances in older adults with dementia and …

[HTML][HTML] Circadian rhythm disruption and retinal dysfunction: a bidirectional link in Alzheimer's disease?

L Carrero, D Antequera, C Municio… - Neural Regeneration …, 2024 - journals.lww.com
Dysfunction in circadian rhythms is a common occurrence in patients with Alzheimer's
disease. A predominant function of the retina is circadian synchronization, carrying …

[HTML][HTML] Remote evaluation of sleep to enhance understanding of early dementia due to Alzheimer's Disease (RESTED-AD): an observational cohort study protocol

J Blackman, HD Morrison, V Gabb, B Biswas, H Li… - BMC geriatrics, 2023 - Springer
Background Sleep and circadian rhythm disorders are well recognised in both AD
(Alzheimer's Disease) dementia and MCI-AD (Mild Cognitive Impairment due to Alzheimer's …

Tailored music listening intervention to reduce sleep disturbances in older adults with dementia: Research protocol

DV Petrovsky, NS Gooneratne, J Bradt… - Research in nursing …, 2020 - Wiley Online Library
Sleep disruption in older adults living with Alzheimer's disease and related dementias
(ADRD) is debilitating and contributes to increased institutionalization, reduced cognitive …