Aptamers have been identified against various targets as a type of chemical or nucleic acid
ligand by systematic evolution of ligands by exponential enrichment (SELEX) with high …

Limited chemical diversity of nucleic acid libraries has long been suspected to be a major
constraining factor in the overall success of SELEX (Systematic Evolution of Ligands by …

Systematic evolution of ligands by exponential enrichment (SELEX) is a well-established
and efficient technology for the generation of oligonucleotides with a high target affinity …

Aptamers are single‐stranded oligonucleotides that bind to targets with high affinity and
selectivity. Their use as molecular recognition elements has emerged as a viable approach …

Aptamers are single stranded oligonucleotides that bind a wide range of biological targets.
Although aptamers can be isolated from pools of random sequence oligonucleotides using …

For many years, different probing techniques have mainly relied on antibodies for molecular
recognition. However, with the discovery of aptamers, this has changed. The science …

The nucleobases comprising DNA and RNA aptamers provide considerably less chemical
diversity than protein-based ligands, limiting their versatility. The introduction of novel …

We report here a few Zika NS1-binding ssDNA aptamers selected using the conventional
SELEX protocol, and their application in an ELISA assay for sensitive diagnosis of Zika NS1 …

This review is intended to guide the novice in aptamer research and development to
understand virtually all of the aptamer development options and currently available assay …

Since they were first reported by two independent research groups 1, 2 in 1990, aptamers
have been widely used in analytical detection, separation, diagnostics, imaging, and …