Genomic imprinting in mammals

DP Barlow, MS Bartolomei - Cold Spring Harbor …, 2014 - cshperspectives.cshlp.org
Genomic imprinting affects a subset of genes in mammals and results in a monoallelic,
parental-specific expression pattern. Most of these genes are located in clusters that are …

[HTML][HTML] X-inactivation, imprinting, and long noncoding RNAs in health and disease

JT Lee, MS Bartolomei - Cell, 2013 - cell.com
X chromosome inactivation and genomic imprinting are classic epigenetic processes that
cause disease when not appropriately regulated in mammals. Whereas X chromosome …

Human microRNA hsa-miR-296-5p suppresses enterovirus 71 replication by targeting the viral genome

Z Zheng, X Ke, M Wang, S He, Q Li, C Zheng… - Journal of …, 2013 - Am Soc Microbiol
ABSTRACT Enterovirus 71 (EV71) has emerged as a major cause of neurological disease
following the near eradication of poliovirus. Accumulating evidence suggests that …

[HTML][HTML] Long noncoding RNA functionality in imprinted domain regulation

WA MacDonald, MRW Mann - PLoS genetics, 2020 - journals.plos.org
Genomic imprinting is a parent-of-origin dependent phenomenon that restricts transcription
to predominantly one parental allele. Since the discovery of the first long noncoding RNA …

[HTML][HTML] Genetics and epigenetics of parathyroid carcinoma

F Marini, F Giusti, G Palmini, G Perigli… - Frontiers in …, 2022 - frontiersin.org
Parathyroid carcinoma (PC) is an extremely rare malignancy, accounting less than 1% of all
parathyroid neoplasms, and an uncommon cause of primary hyperparathyroidism (PHPT) …

[HTML][HTML] Imprinted microRNA gene clusters in the evolution, development, and functions of mammalian placenta

EC Malnou, D Umlauf, M Mouysset, J Cavaillé - Frontiers in genetics, 2019 - frontiersin.org
In mammals, the expression of a subset of microRNA (miRNA) genes is governed by
genomic imprinting, an epigenetic mechanism that confers monoallelic expression in a …

[HTML][HTML] Imprinted long non-coding RNAs in mammalian development and disease

F Di Michele, I Chillón, R Feil - International Journal of Molecular …, 2023 - mdpi.com
Imprinted genes play diverse roles in mammalian development, homeostasis, and disease.
Most imprinted chromosomal domains express one or more long non-coding RNAs …

MicroRNAs as important regulators of the NLRP3 inflammasome

P Zamani, RK Oskuee, SL Atkin… - Progress in biophysics …, 2020 - Elsevier
Inflammasomes are a group of cytosolic multi-protein signaling complexes that regulate
maturation of the interleukin (IL)-1 family cytokines IL-1β and IL-18 through activation of …

[HTML][HTML] Competing endogenous RNA network mediated by circ_3205 in SARS-CoV-2 infected cells

D Barbagallo, CI Palermo, C Barbagallo… - Cellular and Molecular …, 2022 - Springer
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new
member of the Betacoronaviridae family, responsible for the recent pandemic outbreak of …

Differential role of microRNAs in the pathogenesis and treatment of Esophageal cancer

M Hemmatzadeh, H Mohammadi, M Karimi… - Biomedicine & …, 2016 - Elsevier
Esophageal cancer (EC) is the most invasive disease associated with inclusive poor
prognosis. EC usually is found as either adenocarcinoma (EAC) or squamous cell …