During pregnancy, several tightly coordinated and regulated processes take place to enable
proper fetal development and gestational success. The formation and development of the …

Drosophila melanogaster provides a powerful genetic model system in which to investigate
the molecular mechanisms underlying neurodegenerative diseases. In this review, we …

Preeclampsia is a disease of the mother, fetus, and placenta, and the gaps in our
understanding of the complex interactions among their respective disease pathways …

Galectins are a large family of carbohydrate binding proteins with members in nearly every
lineage of multicellular life. Through tandem and en-mass genome duplications, over 15 …

Background The maternal signs of preeclampsia, which include the new onset of high blood
pressure, can occur because of faulty placentation. We theorized that transcriptomic …

Galectins are glycan-binding proteins that regulate innate and adaptive immune responses,
and some confer maternal-fetal immune tolerance in eutherian mammals. A chromosome 19 …

Preeclampsia affects about 3–8% of all pregnancies. It represents a complex and
multifaceted syndrome with at least several potential pathways leading to the development …

BACKGROUND With increasing significance of developmental programming effects
associated with placental dysfunction, more investigations are devoted to improving the …

The first studies suggesting that abnormal expression of galectins is associated with cancer
were published more than 30 years ago. Today, the role of galectins in cancer is relatively …

Fetal growth restriction (FGR) is the most common pregnancy complication in developed
countries. Pregnancies affected by FGR, frequently concur with complications and high risk …