Quantifying brain microstructure with diffusion MRI: Theory and parameter estimation

DS Novikov, E Fieremans, SN Jespersen… - NMR in …, 2019 - Wiley Online Library
We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …

[HTML][HTML] Challenges for biophysical modeling of microstructure

IO Jelescu, M Palombo, F Bagnato… - Journal of Neuroscience …, 2020 - Elsevier
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

Denoising of diffusion MRI using random matrix theory

J Veraart, DS Novikov, D Christiaens, B Ades-Aron… - Neuroimage, 2016 - Elsevier
We introduce and evaluate a post-processing technique for fast denoising of diffusion-
weighted MR images. By exploiting the intrinsic redundancy in diffusion MRI using universal …

Diffusion MRI noise mapping using random matrix theory

J Veraart, E Fieremans… - Magnetic resonance in …, 2016 - Wiley Online Library
Purpose To estimate the spatially varying noise map using a redundant series of magnitude
MR images. Methods We exploit redundancy in non‐Gaussian distributed multidirectional …

Weighted linear least squares estimation of diffusion MRI parameters: strengths, limitations, and pitfalls

J Veraart, J Sijbers, S Sunaert, A Leemans, B Jeurissen - Neuroimage, 2013 - Elsevier
Purpose Linear least squares estimators are widely used in diffusion MRI for the estimation
of diffusion parameters. Although adding proper weights is necessary to increase the …

Rotationally-invariant mapping of scalar and orientational metrics of neuronal microstructure with diffusion MRI

DS Novikov, J Veraart, IO Jelescu, E Fieremans - NeuroImage, 2018 - Elsevier
We develop a general analytical and numerical framework for estimating intra-and extra-
neurite water fractions and diffusion coefficients, as well as neurite orientational dispersion …

Evaluation of the accuracy and precision of the diffusion parameter EStImation with Gibbs and NoisE removal pipeline

B Ades-Aron, J Veraart, P Kochunov, S McGuire… - Neuroimage, 2018 - Elsevier
This work evaluates the accuracy and precision of the Diffusion parameter EStImation with
Gibbs and NoisE Removal (DESIGNER) pipeline, developed to identify and minimize …

Microstructural imaging of the human brain with a 'super-scanner': 10 key advantages of ultra-strong gradients for diffusion MRI

DK Jones, DC Alexander, R Bowtell, M Cercignani… - NeuroImage, 2018 - Elsevier
The key component of a microstructural diffusion MRI 'super-scanner'is a dedicated high-
strength gradient system that enables stronger diffusion weightings per unit time compared …

Constrained optimization of gradient waveforms for generalized diffusion encoding

J Sjölund, F Szczepankiewicz, M Nilsson… - Journal of magnetic …, 2015 - Elsevier
Diffusion MRI is a useful probe of tissue microstructure. The conventional diffusion encoding
sequence, the single pulsed field gradient, has recently been challenged as more general …

One diffusion acquisition and different white matter models: how does microstructure change in human early development based on WMTI and NODDI?

IO Jelescu, J Veraart, V Adisetiyo, SS Milla, DS Novikov… - Neuroimage, 2015 - Elsevier
White matter microstructural changes during the first three years of healthy brain
development are characterized using two different models developed for limited clinical …