Nonsense‐mediated mRNA decay (NMD) was originally coined to define a quality control
mechanism that targets mRNAs with truncated open reading frames due to the presence of a …

Nonsense-mediated mRNA decay (NMD) has traditionally been described as a quality
control system that rids cells of aberrant mRNAs with crippled protein coding potential …

Nonsense-mediated decay (NMD) was first described as a quality-control mechanism that
targets and rapidly degrades aberrant mRNAs carrying premature termination codons …

Spermatogenesis is a cell differentiation process that ensures the production of fertilizing
sperm, which ultimately fuse with an egg to form a zygote. Normal spermatogenesis relies …

During transcription, most eukaryotic genes generate multiple alternative cleavage and
polyadenylation (APA) sites, leading to the production of transcript isoforms with variable …

Nonsense-mediated messenger RNA decay (NMD) represents one of the main surveillance
pathways used by eukaryotic cells to control the quality and abundance of mRNAs and to …

Background Nonsense-mediated mRNA decay (NMD) was originally conceived as an
mRNA surveillance mechanism to prevent the production of potentially deleterious truncated …

Nonsense-mediated mRNA decay (NMD) is a highly conserved post-transcriptional
regulatory mechanism of gene expression in eukaryotes. Originally, NMD was identified as …

Traditional genome-wide scans for positive selection have mainly uncovered selective
sweeps associated with monogenic traits. While selection on quantitative traits is much more …

The nonsense-mediated mRNA decay (NMD) pathway functions to degrade both abnormal
and wild-type mRNAs. NMD is essential for viability in most organisms, but the molecular …