Clinical recommendations for pain, sedation, withdrawal and delirium assessment in critically ill infants and children: an ESPNIC position statement for healthcare …

J Harris, AS Ramelet, M van Dijk, P Pokorna… - Intensive care …, 2016 - Springer
Background This position statement provides clinical recommendations for the assessment
of pain, level of sedation, iatrogenic withdrawal syndrome and delirium in critically ill infants …

Skin‐to‐skin care for procedural pain in neonates

C Johnston, M Campbell‐Yeo, T Disher… - Cochrane Database …, 2017 - cochranelibrary.com
Background Skin‐to‐skin care (SSC), often referred to as' kangaroo care'(KC) due to its
similarity with marsupial behaviour of ventral maternal‐infant contact, is one non …

The influence of pain, agitation, and their management on the immature brain

C McPherson, SP Miller, M El-Dib, AN Massaro… - Pediatric …, 2020 - nature.com
Preterm infants are exposed to frequent painful procedures and agitating stimuli over the
many weeks of their hospitalization in the neonatal intensive care unit (NICU). The adverse …

Pain management in newborns

RW Hall, KJS Anand - Clinics in perinatology, 2014 - perinatology.theclinics.com
Routine assessment and management of neonatal pain has evolved to become an
important therapeutic goal in the twenty-first century. During the twentieth century, however …

Assessment and management of pain in preterm infants: a practice update

M Campbell-Yeo, M Eriksson, B Benoit - Children, 2022 - mdpi.com
Infants born preterm are at a high risk for repeated pain exposure in early life. Despite valid
tools to assess pain in non-verbal infants and effective interventions to reduce pain …

Neonatal pain, parenting stress and interaction, in relation to cognitive and motor development at 8 and 18 months in preterm infants

RE Grunau, MF Whitfield, J Petrie-Thomas, AR Synnes… - Pain, 2009 - Elsevier
Procedural pain in the neonatal intensive care unit triggers a cascade of physiological,
behavioral and hormonal disruptions which may contribute to altered neurodevelopment in …

Neonatal pain-related stress predicts cortical thickness at age 7 years in children born very preterm

M Ranger, CMY Chau, A Garg, TS Woodward, MF Beg… - PloS one, 2013 - journals.plos.org
Background Altered brain development is evident in children born very preterm (24–32
weeks gestational age), including reduction in gray and white matter volumes, and thinner …

Eight years later, are we still hurting newborn infants?

DWE Roofthooft, SHP Simons, KJS Anand, D Tibboel… - Neonatology, 2014 - karger.com
Objective: To study whether new pharmacological and nonpharmacological guidelines
lowered numbers of painful procedures in neonates and changed the amount and frequency …

Early repetitive pain in preterm infants in relation to the developing brain

M Ranger, RE Grunau - Pain management, 2014 - Taylor & Francis
Infants born preterm (< 37 weeks of gestation) are particularly vulnerable to procedural
stress and pain exposure during neonatal intensive care, at a time of rapid and complex …

Prevention and management of procedural pain in the neonate: an update

E Keels, N Sethna, KL Watterberg, JJ Cummings… - …, 2016 - publications.aap.org
Background Neonates are frequently subjected to painful procedures, with the most
immature infants receiving the highest number of painful events. 3,–5 Despite …