Clinical, pathophysiologic, genetic, and therapeutic progress in primary bilateral macronodular adrenal hyperplasia

J Bertherat, I Bourdeau, L Bouys… - Endocrine …, 2023 - academic.oup.com
Patients with primary bilateral macronodular adrenal hyperplasia (PBMAH) usually present
bilateral benign adrenocortical macronodules at imaging and variable levels of cortisol …

ACTH-independent macronodular adrenal hyperplasia

A Lacroix - Best practice & research Clinical endocrinology & …, 2009 - Elsevier
Adrenocorticotropic hormone-(ACTH-) independent macronodular adrenal hyperplasia
(AIMAH) is an infrequent cause of Cushing's syndrome (CS). AIMAH presents as incidental …

[HTML][HTML] ARMC5 Mutations in Macronodular Adrenal Hyperplasia with Cushing's Syndrome

G Assié, R Libé, S Espiard, M Rizk-Rabin… - … England Journal of …, 2013 - Mass Medical Soc
Background Corticotropin-independent macronodular adrenal hyperplasia may be an
incidental finding or it may be identified during evaluation for Cushing's syndrome. Reports …

Potassium channel mutant KCNJ5 T158A expression in HAC-15 cells increases aldosterone synthesis

K Oki, MW Plonczynski, M Luis Lam… - …, 2012 - academic.oup.com
Primary aldosteronism is the most common cause of secondary hypertension, most
frequently due to an aldosterone-producing adenoma or idiopathic hyperaldosteronism …

Aberrant G‐protein coupled receptor expression in relation to adrenocortical overfunction

A Lacroix, I Bourdeau, A Lampron… - Clinical …, 2010 - Wiley Online Library
The aberrant adrenal expression and function of one or several G‐protein coupled receptors
can lead to cell proliferation and abnormal regulation of steroidogenesis in unilateral …

[HTML][HTML] Diagnosis and management of primary bilateral macronodular adrenal hyperplasia

DA Vassiliadi, S Tsagarakis - Endocrine-Related Cancer, 2019 - erc.bioscientifica.com
Primary bilateral macronodular adrenal hyperplasia (PBMAH) is a highly heterogeneous
entity. The incidental identification of an increasing number of cases has shifted its clinical …

[PDF][PDF] Extracellular matrix modulates the biological effects of melatonin in mesenchymal stem cells

F He, X Liu, K Xiong, S Chen, L Zhou… - Journal of …, 2014 - researchgate.net
Why IVF pregnancy rates decline sharply after age 43 is unknown. In this study, we
compared granulosa cell (GC) function in young oocyte donors (nZ31, ages 21–29), middle …

Adrenocortical hyperplasia: A multifaceted disease

I Bourdeau, S Parisien-La Salle, A Lacroix - Best Practice & Research …, 2020 - Elsevier
Adrenocortical hyperplasia may develop in different contexts. Primary adrenal hyperplasia
may be secondary to primary bilateral macronodular adrenocortical hyperplasia (PBMAH) or …

[HTML][HTML] Sexual dimorphism and thyroid dysfunction: a matter of oxidative stress?

RS Fortunato, ACF Ferreira, F Hecht… - Journal of …, 2014 - joe.bioscientifica.com
Testis development from an indifferent gonad is a critical step in embryogenesis. A hallmark
of testis differentiation is sex-specific vascularization that occurs as endothelial cells migrate …

Primary bilateral macronodular adrenal hyperplasia

A De Venanzi, GA Alencar, I Bourdeau… - Current Opinion in …, 2014 - journals.lww.com
Recent findings indicate that bilateral macronodular adrenal hyperplasia is more frequently
genetically determined than previously believed. Considering the role of paracrine …