Syntheses of nucleoside triphosphates

K Burgess, D Cook - Chemical Reviews, 2000 - ACS Publications
Nucleoside triphosphates (NTPs and dNTPs, Figure 1) have important therapeutic and
diagnostic applications. Experience with syntheses of these compounds, and discussions …

Chemistry and developments of fluorinated carbohydrates

T Tsuchiya - Advances in carbohydrate chemistry and biochemistry, 1990 - Elsevier
Publisher Summary This chapter presents a review about the chemistry and developments
of fluorinated carbohydrates. Because of the high C–F bond energy, glycosyl fluorides are …

A system for rapid DNA sequencing with fluorescent chain-terminating dideoxynucleotides

JM Prober, GL Trainor, RJ Dam, FW Hobbs… - Science, 1987 - science.org
A DNA sequencing system based on the use of a novel set of four chain-terminating
dideoxynucleotides, each carrying a different chemically tuned succinylfluorescein dye …

Short cycle methods for sequencing polynucleotides

SN Lapidus, PR Buzby, T Harris - US Patent 7,169,560, 2007 - Google Patents
US7169560B2 - Short cycle methods for sequencing polynucleotides - Google Patents
US7169560B2 - Short cycle methods for sequencing polynucleotides - Google Patents …

Methods and apparatus for analyzing polynucleotide sequences by asynchronous base extension

S Quake, I Braslavsky, B Hebert, E Kartalov - US Patent 7,297,518, 2007 - Google Patents
The invention provides methods and apparatus for analyzing polynucleotide sequences by
asynchronous base extension. Some applications of the invention utilize total internal …

[PDF][PDF] Palladium-catalyzed alkylations in aqueous media

AL Casalnuovo, JC Calabrese - Journal of the American Chemical …, 1990 - ACS Publications
Conclusion. The crystal structures we have reported, in con-junction with prior evidence in
the literature, support the notion that macrocyclization of ethylene sulfide oligomers is not an …

Method of determining the nucleotide sequence of oligonucleotides and DNA molecules

P Williams, TJ Taylor, DJB Williams, I Gould… - US Patent …, 2010 - Google Patents
The present invention relates to a novel method for analyzing nucleic acid sequences based
on real-time detection of DNA poly-merase-catalyzed incorporation of each of the four …

Effects of 2-Chloro-9-(2-deoxy-2-fluoro-β-d-arabinofuranosyl)adenine on K562 Cellular Metabolism and the Inhibition of Human Ribonucleotide Reductase and DNA …

WB Parker, SC Shaddix, CH Chang, EL White… - Cancer research, 1991 - AACR
Chloro-9-(2-deoxy-2-fluoro-β-d-arabinofuranosyl)-adenine (Cl-F-ara-A) has activity against
the P388 tumor in mice on several different schedules. Biochemical studies with a chronic …

Nonradioactive labeling of oligonucleotides in vitro with the hapten digoxigenin by tailing with terminal transferase

GG Schmitz, T Walter, R Seibl, C Kessler - Analytical biochemistry, 1991 - Elsevier
A procedure for the nonradioactive labeling of oligonucleotides with the hapten digoxigenin
(DIG) has been developed. The label is introduced by enzymatic tailing of the 3′-end. Two …

Short cycle methods for sequencing polynucleotides

S Lapidus, PR Buzby, T Harris - US Patent 7,897,345, 2011 - Google Patents
US7897345B2 - Short cycle methods for sequencing polynucleotides - Google Patents
US7897345B2 - Short cycle methods for sequencing polynucleotides - Google Patents Short …