Biocatalysis has undergone revolutionary progress in the past century. Benefited by the
integration of multidisciplinary technologies, natural enzymatic reactions are constantly …

l-Tryptophan, l-phenylalanine, and l-tyrosine are aromatic amino acids (AAAs) that are used
for the synthesis of proteins and that in plants also serve as precursors of numerous natural …

In the past decade, the asymmetric synthesis of chiral nonracemic isoquinoline alkaloids, a
family of natural products showing a wide range of structural diversity and biological and …

Benzylisoquinoline alkaloids (BIAs) are a diverse family of plant-specialized metabolites that
include the pharmaceuticals codeine and morphine and their derivatives. Microbial …

Cyanobacteria are photosynthetic prokaryotes showing great promise as biocatalysts for the
direct conversion of CO 2 into fuels, chemicals, and other value-added products. Introduction …

Aromatic amino acids are precursors of numerous plant secondary metabolites with diverse
biological functions. Many of these secondary metabolites are already being used as active …

Natural products have played a prominent role in the history of organic chemistry, and they
continue to be important as drugs, biological probes, and targets of study for synthetic and …

The ongoing trends to process improvements, cost reductions and increasing quality, safety,
health and environment requirements of industrial chemical transformations have …

Natural products and their derivatives play an important role in modern healthcare as
frontline treatments for many diseases and as inspiration for chemically synthesized …

A common strategy of metabolic engineering is to increase the endogenous supply of
precursor metabolites to improve pathway productivity. The ability to further enhance …