Parabrachial neurons promote nociplastic pain

RD Palmiter - Trends in Neurosciences, 2024 - cell.com
The parabrachial nucleus (PBN) in the dorsal pons responds to bodily threats and transmits
alarm signals to the forebrain. Parabrachial neuron activity is enhanced during chronic pain …

[HTML][HTML] VLK drives extracellular phosphorylation of EphB2 to govern the EphB2-NMDAR interaction and injury-induced pain

KD Srikanth, H Elahi, P Chander, HR Washburn… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Phosphorylation of hundreds of protein extracellular domains is mediated by two kinase
families, yet the significance of these kinases is underexplored. Here, we find that the …