Tm-enhanced blocking oligonucleotides and baits for improved target enrichment and reduced off-target selection

MA Behlke, JR Havens, M Jarosz, Z Zwirko… - US Patent …, 2019 - Google Patents
US10266889B2 - Tm-enhanced blocking oligonucleotides and baits for improved target
enrichment and reduced off-target selection - Google Patents US10266889B2 - Tm-enhanced …

Tm-enhanced blocking oligonucleotides and baits for improved target enrichment and reduced off-target selection

MA Behlke, JR Havens, M Jarosz, Z Zwirko… - US Patent …, 2023 - Google Patents
2017-03-30 Assigned to FOUNDATION MEDICINE, INC. reassignment FOUNDATION
MEDICINE, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

Tm-enhanced blocking oligonucleotides and baits for improved target enrichment and reduced off-target selection

MA Behlke, JR Havens - US Patent 11,566,283, 2023 - Google Patents
US11566283B2 - Tm-enhanced blocking oligonucleotides and baits for improved target
enrichment and reduced off-target selection - Google Patents US11566283B2 - Tm-enhanced …

Sample analysis, presence determination of a target sequence

H Metsky, A Gnirke, C Matranga, D Park… - US Patent …, 2022 - Google Patents
The present invention provides a combination of genomic and computational technologies
to provide rapid, portable sample analysis for sequencing or identifying a target sequence …

System and method for the detection and treatment of infection by a microbial agent associated with HIV infection

L Montagnier - US Patent 9,580,758, 2017 - Google Patents
6,015,691 A 1/2000 Walker et al. least one immunostimulant, eg, which directly or indirectly
6,168,915 B1 1/2001 Scholl et al. increases levels of immunostimulatory cytokines in the …

System and method for the detection and treatment of infection by a microbial agent associated with HIV infection

L Montagnier - US Patent 10,525,066, 2020 - Google Patents
(57) ABSTRACT A method of treating a patient, comprising administering at least one
antibiotic, eg, doxycycline and ciprofloxacin, sufficient to substantially treat an intracellular …

High throughput discovery of new genes from complex mixtures of environmental microbes

V Beilinson, J Jones, J Parks, RE Thayer… - US Patent …, 2023 - Google Patents
Compositions and methods for isolating new variants of known gene sequences are
provided. The methods find use in identifying variants, particularly homologs, in complex …

Methods and compositions to identify novel crispr systems

AB Crawley, JR Henriksen, M Moore, RE Thayer - 2019 - Google Patents
Compositions and methods for isolating new variants of known clustered regularly-
interspaced short palindromic repeat (CRISPR) RNA-guided nuclease (RGN) genes and …

High throughput discovery of new genes from complex mixtures of environmental microbes

V Beilinson, J Jones, J Parks, RE Thayer… - US Patent …, 2021 - Google Patents
Compositions and methods for isolating new variants of known gene sequences are
provided. The methods find use in identifying variants, particularly homologs, in complex …

Partitioning of DNA sequencing libraries into host and microbial components

CD Bustamante, ML Carpenter - US Patent 10,954,509, 2021 - Google Patents
Described herein is a method for isolating microbial DNA from a sample that comprises host
DNA and microbial DNA. In some embodiments, the method may comprise: obtaining a …