Insect antimicrobial peptides: potential weapons to counteract the antibiotic resistance

MD Manniello, A Moretta, R Salvia, C Scieuzo… - Cellular and Molecular …, 2021 - Springer
Misuse and overuse of antibiotics have contributed in the last decades to a phenomenon
known as antibiotic resistance which is currently considered one of the principal threats to …

Antimicrobial peptides: A potent alternative to antibiotics

M Rima, M Rima, Z Fajloun, JM Sabatier, B Bechinger… - Antibiotics, 2021 - mdpi.com
Antimicrobial peptides constitute one of the most promising alternatives to antibiotics since
they could be used to treat bacterial infections, especially those caused by multidrug …

Synergistic effect of two antimicrobial peptides, Nisin and P10 with conventional antibiotics against extensively drug-resistant Acinetobacter baumannii and colistin …

A Jahangiri, A Neshani, SA Mirhosseini, K Ghazvini… - Microbial …, 2021 - Elsevier
Background Infections caused by drug-resistant strains of Acinetobacter baumannii and
Pseudomonas aeruginosa are now a global problem that requires the immediate …

Protective barriers provided by the epidermis

S de Szalay, PW Wertz - International Journal of Molecular Sciences, 2023 - mdpi.com
The skin is the largest organ of the body and consists of an epidermis, dermis and
subcutaneous adipose tissue. The skin surface area is often stated to be about 1.8 to 2 m2 …

Therapeutic strategies against potential antibiofilm targets of multidrug‐resistant Acinetobacter baumannii

V Kaushik, M Tiwari, R Joshi… - Journal of Cellular …, 2022 - Wiley Online Library
Acinetobacter baumannii is the causative agent of various hospital‐acquired infections.
Biofilm formation is one of the various antimicrobial resistance (AMR) strategies and is …

Antimicrobial and amyloidogenic activity of peptides. Can antimicrobial peptides be used against SARS-CoV-2?

SR Kurpe, SY Grishin, AK Surin, AV Panfilov… - International Journal of …, 2020 - mdpi.com
At present, much attention is paid to the use of antimicrobial peptides (AMPs) of natural and
artificial origin to combat pathogens. AMPs have several points that determine their …

Antimicrobial Peptide Cec4 Eradicates the Bacteria of Clinical Carbapenem-Resistant Acinetobacter baumannii Biofilm

W Liu, Z Wu, C Mao, G Guo, Z Zeng, Y Fei… - Frontiers in …, 2020 - frontiersin.org
The drug resistance rate of Acinetobacter baumannii increases year on year, and the drugs
available for the treatment of carbapenem-resistant A. baumannii (CRAB) infection are …

Antimicrobial Peptide Cec4 Eradicates Multidrug-Resistant Acinetobacter baumannii in vitro and in vivo

J Peng, Y Wang, Z Wu, C Mao, L Li, H Cao… - Drug Design …, 2023 - Taylor & Francis
Introduction Acinetobacter baumannii has become a major difficulty in the treatment of
bacteria-associated infection. The previously reported antimicrobial peptide Cec4 exhibited …

An Update on the Therapeutic Potential of Antimicrobial Peptides against Acinetobacter baumannii Infections

K Rangel, GC Lechuga, DW Provance Jr, CM Morel… - Pharmaceuticals, 2023 - mdpi.com
The rise in antibiotic-resistant strains of clinically important pathogens is a major threat to
global health. The World Health Organization (WHO) has recognized the urgent need to …

Specific egg yolk immunoglobulin as a promising non-antibiotic biotherapeutic product against Acinetobacter baumannii pneumonia infection

A Jahangiri, P Owlia, I Rasooli, J Salimian… - Scientific reports, 2021 - nature.com
Acinetobacter baumannii is a serious health threat with a high mortality rate. We have
already reported prophylactic effects of IgYs raised against OmpA and Omp34 as well as …